Can a probiotic shield kids from antibiotic side effects?
NCT ID NCT07015736
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a probiotic (Saccharomyces boulardii) along with a common antibiotic can protect the gut bacteria of children aged 4 to 12 being treated for ear or sinus infections. The goal is to see if it reduces antibiotic-associated diarrhea and limits the spread of antibiotic-resistant genes. One hundred children will receive either the antibiotic alone or with the probiotic for 10 to 21 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Saccharomyces boulardii CNCM I-745 (a probiotic yeast)
What this could lead to
If it works, this could show that taking a probiotic alongside antibiotics helps prevent diarrhea and keeps the gut microbiome healthy in children.
What could go wrong
This is a small, early-phase study with only 100 children, so results may not apply to everyone. The probiotic might not reduce diarrhea or could cause side effects like bloating.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE OTITIS MEDIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Acibadem Univsersity Faculty of Medicine
Istanbul, Turkey (Türkiye)
-
Eskisehir Osmangazi University
Eskişehir, 26040, Turkey (Türkiye)
-
Sancaktepe Şehit Prof.Dr. İlhan Varank Training and Research Hospital
Istanbul, Turkey (Türkiye)
-
Şişli Hamidiye Etfal Training and Research Hospital
Istanbul, Turkey (Türkiye)