Hallucinogen abuse
MONDO:0001585A substance abuse that involves the recurring use of hallucinogenic drugs despite negative consequences.
107 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Prizes for parents: can small rewards keep teens out of trouble?
Disease control CompletedThis study tested whether giving caregivers prize draws for attending court hearings, treatment sessions, and probation meetings could reduce substance use and delinquency in teens already in juvenile drug court. Fifty-three teens aged 13-17 and their caregivers took part. The go…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Giving people a choice in HIV care may boost treatment uptake after jail
Disease control CompletedThis study tests two approaches to help people recently involved with the justice system start HIV prevention or treatment and substance use care. One group gets standard patient navigation; the other can choose from a menu of services including in-person clinics, a mobile health…
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Simple support strategies may help curb hepatitis c in appalachia
Disease control CompletedThis study tests whether offering peer support, small incentives, telehealth visits, or prepaid phones helps people with hepatitis C and substance use disorders get linked to medical care. Participants are adults in Appalachia who have tested positive for hepatitis C and have a h…
Phase: NA • Sponsor: Carilion Clinic • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Community-Led recovery: could indigenous wisdom curb substance use?
Disease control CompletedThis study tests a 6-week group program called Indigenous Recovery Planning (IRP) for American Indian adults with alcohol or drug use disorder. The program is led by trained community members and includes culturally adapted exercises to prevent relapse. Researchers want to see if…
Phase: NA • Sponsor: Montana State University • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Web therapy for addiction shows promise in native communities
Disease control CompletedThis study tested a web-based addiction treatment program that was culturally adapted for American Indians and Alaska Natives. 53 adults in outpatient treatment used the program for 12 weeks. The goal was to see if it helped them stay away from drugs and alcohol and to decide if …
Phase: NA • Sponsor: New York State Psychiatric Institute • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Mindfulness may keep women in addiction treatment longer
Disease control CompletedThis study tested a mindfulness program designed for women in residential treatment for substance use disorders. The program, called Mindfulness-Based Relapse Prevention for Women (MBRP-W), teaches stress management skills to help women stay in treatment and avoid relapse. Resear…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can a coach in the ER help people beat addiction?
Disease control CompletedThis study tested whether peer recovery coaches in emergency departments can help people with substance use disorders connect to treatment and support. 144 adults were randomly assigned to get in-person coaching, coaching via video call, or just a list of resources. Researchers f…
Phase: NA • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Smartphone app and digital pill aim to boost HIV prevention in substance users
Disease control CompletedThis study tested a digital pill and smartphone app to help people with substance use disorders take their HIV prevention medication (PrEP) consistently. Thirty HIV-negative men who have sex with men and have moderate to severe substance use disorder participated. They used a dig…
Phase: PHASE3 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 26, 2026 18:31 UTC
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Mindfulness program shows promise in preventing relapse, but tiny study limits conclusions
Prevention CompletedThis small pilot study tested an 8-week mindfulness and meditation program in 3 adults with substance use disorders. Participants reported lower stress and improved mindfulness after the program. One person stayed sober long-term, while two relapsed within a year. The study shows…
Sponsor: Bout Me Healing • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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New online tool helps rural parents struggling with opioids
Prevention CompletedThis study tested an online parenting program called Family Check-Up Online for rural families where a parent may misuse opioids. 356 parents of young children (18 months to 5 years) took part. The program aimed to improve parenting skills, reduce stress and depression, and preve…
Phase: NA • Sponsor: University of Oregon • Aim: Prevention
Last updated Jun 27, 2026 09:00 UTC
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Zapping the brain with microcurrents may curb cravings — a trial puts it to the test
Symptom relief CompletedThis pilot trial tests whether adding microcurrent neurofeedback (MCN) to standard residential treatment helps adults with substance use disorder more than standard care alone. MCN uses scalp sensors to deliver barely perceptible electrical pulses tailored to each person's brain …
Phase: NA • Sponsor: University of Alabama, Tuscaloosa • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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Can a smartphone app help people stay sober? new study says maybe.
Symptom relief CompletedThis study tested whether a digital mindfulness app is practical and acceptable for people in early recovery from substance use disorders. 36 participants were randomly assigned to standard group therapy alone or standard therapy plus the app for 8 weeks. The main goal was to see…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New therapy shows promise for healing war wounds in rwanda
Symptom relief CompletedThis study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…
Phase: NA • Sponsor: Alexandros Lordos, PhD • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Personalized craving scale shows promise for addiction treatment
Symptom relief CompletedThis study tested whether adding a personalized therapy scale to standard treatment helps reduce cravings in people with substance use disorders or behavioral addictions like gambling. 151 adults seeking outpatient care participated. The approach aimed to tailor treatment to each…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Can online mindfulness or CBT ease pandemic depression and drug use?
Symptom relief CompletedThis study tested two remotely delivered programs—mindfulness-based cognitive therapy and internet-based cognitive behavioral therapy—against standard remote monitoring alone for reducing depression and substance use related to COVID-19 stress. 113 adults from a health system par…
Phase: NA • Sponsor: Cambridge Health Alliance • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Breathwork breakthrough? SKY program may ease cravings in recovery
Symptom relief CompletedThis study tested a breathing and meditation program called SKY Recovery in 100 people recovering from substance use disorder at a residential center. Participants either took the program right away or after a delay. Researchers measured changes in emotion regulation, cravings, a…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Can online therapy and a buddy help beat addiction?
Symptom relief CompletedThis study looked at whether an online cognitive behavioral therapy program, called Breaking Free Online, helps people with substance use disorder cut back on their drug or alcohol use. About 200 adults from an outpatient addiction program took part. Some got standard care with g…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New telehealth therapy targets loneliness to curb substance use in veterans
Symptom relief CompletedThis study tested a special type of talk therapy (cognitive-behavioral therapy, or CBT) delivered over telehealth to help veterans who feel lonely and struggle with substance use. The goal was to see if the program was practical and well-liked by participants. Thirty-six veterans…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Night help for moms in recovery: can respite care improve sleep and Well-Being?
Symptom relief CompletedThis study tested whether providing overnight infant care and parenting support helps new mothers with substance use disorder living in residential treatment programs. 41 mothers participated, and researchers measured how many enrolled, completed the program, and gave feedback. T…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New manual seeks to boost black representation in addiction trials
Knowledge-focused CompletedThis completed study worked with 65 African American/Black adults who use cocaine or other illicit substances to develop a manual called I-DREM. The goal was to gather their feedback on how to improve recruitment and retention in substance use disorder clinical trials. Participan…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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New brain scans could unlock secrets of drug addiction
Knowledge-focused CompletedThis study aims to create and improve cognitive tasks used during functional MRI scans to better understand how drugs affect the brain. It involves 525 healthy volunteers, including both drug users and non-users, aged 18 to 65. Participants perform tasks like memory tests or reac…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Hospital study reveals who gets help for addiction in the ER
Knowledge-focused CompletedThis study looked back at the records of 652 patients who were seen in the emergency department of a French hospital and then referred to a special addiction liaison team. The goal was to understand the social and medical backgrounds of these patients. The findings could help hos…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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App aims to support recovery for justice-involved individuals
Knowledge-focused CompletedThis study tested whether a mobile app could help people on probation or parole who are receiving treatment for substance use disorder. 31 adults used the app alongside their usual care. Researchers measured how easy the app was to use and how satisfied participants were with it.
Phase: NA • Sponsor: Friends Research Institute, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Can training reduce stigma in healthcare? new study tests Anti-Bias program
Knowledge-focused CompletedThis study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can smartphone apps help fight addiction in primary care? large study tests new approach.
Knowledge-focused CompletedThis study looked at the best ways to bring FDA-approved digital treatments (reSET and reSET-O) for opioid and other substance use disorders into primary care clinics. Over 18,000 adults who screened positive for substance use took part. Researchers tested whether health coaching…
Phase: NA • Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can video therapy help families cope with psychosis and addiction?
Knowledge-focused CompletedThis study tested a program called CRAFT-EP, which helps families support a relative with early psychosis and substance use (like alcohol or cannabis). The program was delivered entirely through video calls. Researchers measured family members' depression and anxiety to see if th…
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New study checks if depression scale works for those with addiction
Knowledge-focused CompletedThis study looked at whether a questionnaire called the Behavioral Activation for Depression Scale (BADS) is a good tool for measuring depression-related behaviors in people with substance use disorders. Researchers analyzed answers from 289 adults receiving treatment for substan…
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New spanish screening tool could help catch substance abuse early
Knowledge-focused CompletedThis study tested a Spanish-language electronic screening tool called TAPS-ESP to identify tobacco, alcohol, prescription drug, and illicit substance use in primary care. About 1,000 Spanish-speaking adults from a clinic participated. The goal was to see if the tool accurately de…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:15 UTC
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AI coaching for addiction counselors? study tests new approach
Knowledge-focused CompletedThis study tested a new way to help addiction treatment clinics use an AI platform that coaches counselors in evidence-based techniques. Researchers worked with 479 leaders and staff from state agencies and clinics in Oregon and Indiana. The goal was to see if this strategy impro…
Phase: NA • Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can changing clinic policies and training doctors reduce stigma around addiction?
Knowledge-focused CompletedThis study tested whether combining a policy change with professional training can reduce stigma toward substance use in mental health clinics. Twelve providers from two sites participated. The goal was to see if the combined approach improves how often substance use is addressed…
Phase: NA • Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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New program aims to teach teens about drug risks
Knowledge-focused CompletedThis study tested an educational program designed to improve teenagers' knowledge and behavior around substance abuse. The program used a model called the Behavior Change Wheel to guide learning. Researchers worked with 226 adolescents aged 10 to 18 who had not received similar e…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC