Glaucoma

This early study tests whether QLS-111 eye drops can improve blood flow to the back of the eye in people with non-proliferative diabetic retinopathy or certain types of glaucoma. Fourteen participants will use the drops twice daily for two weeks. The main goal is to measure chang…

This study reviews 100 patients with open-angle glaucoma who had two minimally invasive surgeries (Hydrus microstent and iTrack canaloplasty) along with cataract surgery. Researchers want to see if this combination lowers eye pressure and reduces the need for glaucoma medications…

This study tests a new laser procedure called Direct Selective Laser Trabeculoplasty (DSLT) in 40 ethnic Chinese patients with glaucoma or high eye pressure. The laser aims to improve fluid drainage in the eye and reduce pressure. Researchers will check if the treatment is safe a…

This study follows 100 adults with primary open-angle glaucoma who had a goniotomy procedure using the C-Rex surgical instrument. The goal is to see how well the surgery lowers intraocular pressure and reduces the need for glaucoma medications over 12 months. Researchers will als…

This study is testing a device called XEN63, a small implant placed in the eye to help drain fluid and lower pressure in people with glaucoma. Researchers will follow 96 patients for 24 months to see if the implant safely reduces eye pressure and the need for daily eye drops. The…

This study tests whether long-term, mild electrical stimulation using a home device can safely slow vision loss in people with open-angle glaucoma. About 45 adults with moderate vision damage will use the device regularly. The goal is to see if this approach can protect the optic…

This early study tests a new drainage device for people with glaucoma, a condition where pressure builds up in the eye. The device is designed to self-adjust to help lower eye pressure. Ten participants will be followed to see if the device is safe and effective at reducing press…

This study tests a new device called the VividWhite Glaucoma Implant, which is surgically placed in the eye to help lower pressure in people with glaucoma. Sixty-five participants will be followed for 12 months to see if the implant safely reduces eye pressure and lessens the nee…

This pilot study tests whether placing a slow-release steroid insert (Yutiq) during glaucoma drainage surgery helps reduce scarring and keeps eye pressure lower. About 5 adults with glaucoma will receive the implant along with their surgery. Researchers will compare their pressur…

This phase 2 trial tests a small implant (NT-501) placed inside the eye to protect nerve cells and slow vision loss in people with glaucoma. 54 participants will either get the implant or a sham surgery, and their vision will be tracked for 2 years. The implant releases a protein…

This phase 2 trial tests whether an implant placed in the eye can slow vision loss in people with glaucoma. The implant releases a protein that may protect nerve cells. Thirty participants will receive either the real implant or a sham procedure and be followed for two years.

This study tests two different spots (temporal vs inferior) for a YAG laser iridotomy in people with angle-closure glaucoma. Each patient gets one spot in each eye, and doctors track pressure, symptoms, and complications over six months. The goal is to find which location is safe…

This trial tests a small implant called MINIject that is placed inside the eye to help drain fluid and lower pressure in people with open-angle glaucoma. About 975 adults who have already had cataract surgery are taking part. The goal is to see if the implant safely reduces eye p…

This study follows 23 people who received a special lens implant that slowly releases a glaucoma drug (bimatoprost) during cataract surgery. Researchers want to see if it keeps eye pressure low and vision clear for up to 7 years. The goal is to learn whether this combination devi…

This trial evaluates a new device called the Photobionic IOP Tonometer (PIB) that measures eye pressure without touching the eye or using an air puff. It uses a low-power infrared light and a gentle sound to detect tiny movements on the eye's surface, which a computer analyzes to…

This study tests smart soft contact lenses that measure eye pressure continuously for 24 hours in people with glaucoma and healthy adults. Researchers will check how accurate and comfortable the lenses are compared to standard eye pressure tests. The goal is to improve glaucoma c…

Researchers are testing whether netarsudil eye drops can protect the cornea in people with Fuchs endothelial corneal dystrophy and glaucoma who have cataract surgery. The study enrolls 50 adults aged 40 to 90. Participants use either netarsudil or a placebo drop daily for four we…

This study looks at whether a 12-week home exercise program (cycling and resistance training) can improve vision and quality of life in people with glaucoma. Researchers will measure changes in visual field sensitivity, eye blood flow, and oxygen use. The goal is to see if exerci…

This study tests whether a computer-based AI tool can teach glaucoma patients how to take a visual field test more accurately. The test checks side vision, which is important for monitoring glaucoma. If the tool works, it could lead to more reliable results, fewer repeat visits, …

Researchers are studying whether lowering the pressure inside the eye improves blood flow to the eye in people with glaucoma. The study follows adults with open-angle or chronic angle-closure glaucoma who are scheduled for glaucoma surgery. Using imaging scans, the team measures …

This study looks at how a common glaucoma eye drop (latanoprost with preservatives) changes the natural bacteria living on the eye's surface. Researchers will compare the eye bacteria of 45 newly diagnosed glaucoma patients before and after at least 6 months of treatment. The goa…

This study looks at whether images of the optic nerve head taken at two different eye pressures can predict how glaucoma will change over time. Researchers will compare these strain measurements to actual vision loss in 130 glaucoma patients. The goal is to develop a new biomarke…

This study looks at how common Charles Bonnet Syndrome (CBS) is in people with vision loss from conditions like macular degeneration or glaucoma. CBS causes complex visual hallucinations without mental illness. Researchers will survey 640 participants to measure how often it happ…

This study looks at 116 adults who had glaucoma stent surgery up to 2 years ago. Researchers use a special eye scan (OCT) to check if the tiny stents are in the right position and how that affects eye pressure. The goal is to learn how often stents are misplaced and whether prope…

This study gathers vision data from 100 healthy adults to teach an AI system how normal eyes see. The goal is to make a new eye test that can find problems like glaucoma more accurately. Participants do not receive any treatment, and the results will help improve future diagnosis…

This study follows 300 patients with chronic eye conditions like glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy who recently received treatment. Researchers will measure changes in eye pressure, vision, and other outcomes over time. The goal is to unde…

This study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…