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Eye drops may shield the cornea after cataract surgery

NCT ID NCT06969586

Prevention Sponsor: University Hospital Dubrava Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers are testing whether netarsudil eye drops can protect the cornea in people with Fuchs endothelial corneal dystrophy and glaucoma who have cataract surgery. The study enrolls 50 adults aged 40 to 90. Participants use either netarsudil or a placebo drop daily for four weeks after surgery, and researchers measure corneal cell density and vision.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
netarsudil 0.02% eye drops
What this could lead to
If it works, netarsudil eye drops could become a way to protect the cornea after cataract surgery in people with Fuchs endothelial corneal dystrophy and glaucoma.
What could go wrong
This is a small, short study. The drops may not protect the cornea, and the results may not apply to people with other eye conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The patients with glaucoma and FECD scheduled for cataract surgery.

Ages

40 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age between 40 and 90 years; * diagnosis of FECD and glaucoma; * cataract grade II nuclear/cortical or posterior subcapsular (Lens Opacity Classification System III \[LOCS III\]. Exclusion criteria: * other anterior segment pathology (pseudoexfoliation syndrome, corneal opacities); * ocular surface inflammation; * intraoperative complications (posterior capsular rupture, vitreous loss, IOL not implanted in the capsular bag); * previous ocular trauma or intraocular surgery

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Conditions

The condition(s) this trial relates to.

cataract corneal edema Fuchs' endothelial dystrophy glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataract Fuchs endothelial corneal dystrophy Glaucoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital Dubrava

    Zagreb, Croatia, 10000, Croatia

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