New surgical tool aims to lower eye pressure in glaucoma patients

NCT ID NCT06615661

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study follows 100 adults with primary open-angle glaucoma who had a goniotomy procedure using the C-Rex surgical instrument. The goal is to see how well the surgery lowers intraocular pressure and reduces the need for glaucoma medications over 12 months. Researchers will also track any device-related complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
C-Rex Instrument, a manual ophthalmic surgical device used for goniotomy
What this could lead to
If successful, this could confirm that the C-Rex device is a safe and effective surgical option for lowering eye pressure in glaucoma patients.
What could go wrong
This is an observational study without a comparison group, so results may not prove the device is better than other treatments. Some patients may not achieve the desired pressure reduction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CIRCLE Site 04

    Crossville, Tennessee, 38555, United States

  • CIRCLE Site 07

    Atlanta, Georgia, 30342, United States

  • CIRCLE Site 10

    DeLand, Florida, 32720, United States

  • CIRCLE Site 30

    Brentwood, New York, 11717, United States

  • CIRCLE Site 31

    Rockville Centre, New York, 11570, United States

  • CIRCLE Site 32

    Cape Coral, Florida, 33904, United States

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