New Preservative-Free eye drop could match leading glaucoma treatment

NCT ID NCT07661329

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether a preservative-free version of bimatoprost eye drops works as well as the standard Lumigan drops for lowering eye pressure. About 600 adults with primary open-angle glaucoma or ocular hypertension in both eyes will receive either the new formulation or Lumigan. The study measures eye pressure over time to see if the new drops are non-inferior.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bimatoprost ophthalmic solution 0.01%

What this could lead to

If successful, this could offer a preservative-free alternative to a standard glaucoma treatment, potentially reducing side effects for patients.

What could go wrong

This is a non-inferiority trial, so the new formulation may prove no better than the existing drug. Results are limited to eye pressure reduction, not long-term vision outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ocular hypertension open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced research, LLC

    NOT_YET_RECRUITING

    Boynton Beach, Florida, 33437, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Advanced research, LLC

    NOT_YET_RECRUITING

    Weston, Florida, 33326, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clayton Eye Clinical Research

    NOT_YET_RECRUITING

    Morrow, Georgia, 30260, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Coastal Research Associates, LLC

    NOT_YET_RECRUITING

    Roswell, Georgia, 30076, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Eye research foundation, Inc.

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Houston Eye Associates

    NOT_YET_RECRUITING

    Houston, Texas, 77008, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • National Clinical Trials

    NOT_YET_RECRUITING

    Beverly Hills, California, 90210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • North Bay Eye Associates

    NOT_YET_RECRUITING

    Petaluma, California, 94954, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ophthalmology associate (Eye care)

    NOT_YET_RECRUITING

    St Louis, Missouri, 63131, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Quantum clinical trials

    NOT_YET_RECRUITING

    Miami Beach, Florida, 33140, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • R and R eye research

    NOT_YET_RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rochester Ophthalmological Group

    NOT_YET_RECRUITING

    Rochester, New York, 14618, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tekwani vision center

    NOT_YET_RECRUITING

    St Louis, Missouri, 63128, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The eye care institute

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40206, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • United medical research institute

    NOT_YET_RECRUITING

    Inglewood, California, 90301, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Visionary Eye Research Institute

    NOT_YET_RECRUITING

    Newport Beach, California, 92663, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••