Female stress incontinence

This study is testing a new device called ARTUS® that acts like an artificial muscle to control urine leakage in women with severe stress urinary incontinence. Six women who have not gotten better with other treatments will get the device implanted and be followed for two years. …

This study compares two treatments for stress urinary incontinence (leaking urine when you cough, sneeze, or exercise). One group gets a shot of platelet-rich plasma (PRP) made from their own blood, while the other gets a standard surgical sling. The trial will enroll 42 women an…

This study tests whether a treated umbilical vein graft can effectively treat stress urinary incontinence in women, comparing it to the standard sling made from the patient's own tissue. About 96 women will receive one of the two surgical treatments and be followed for a year. Th…

This study looks at whether giving women a single dose of antibiotics right before a clinic-based urethral bulking procedure (for stress incontinence) can lower their chance of getting a urinary tract infection afterward. About 150 women will be split into two groups: one gets th…

This study looks at whether the position a woman gives birth in (lying on her back, upright, or on her side) can help prevent stress urinary incontinence (leaking urine when coughing or sneezing) after childbirth. Researchers will follow 669 first-time mothers, ages 20-35, who pl…

This study tests whether adding core muscle exercises to standard pelvic floor training can better reduce urinary incontinence. Fifty adults with stress or mixed incontinence will do 12 weeks of exercises, either standard or with core co-activation. Researchers will measure sympt…

This study tests whether injecting a numbing medicine (bupivacaine) into the surgical site during sling surgery for stress urinary incontinence can reduce pelvic and thigh pain after the operation. Sixty women will be randomly assigned to receive either the numbing medicine or a …

This study will test two different pelvic floor exercise techniques in 40 women aged 30-40 with stress urinary incontinence (leaking urine during activities like coughing or exercise). One group will do exercises in gradually harder positions, while the other will use gradually h…

This study investigates whether adding low-intensity shockwave therapy to standard Kegel exercises can better reduce urine leakage in women with stress urinary incontinence. Participants will either do Kegels alone or Kegels plus weekly shockwave sessions for eight weeks. The goa…

This study tests whether suzetrigine, a new painkiller that works on nerves without affecting the brain, can control pain after pelvic surgery as well as standard opioids. 120 women will receive either suzetrigine or opioids, along with common pain relievers. The goal is to see i…

This study tests a device called VTone that uses gentle electrical pulses inside the vagina to strengthen muscles and reduce stress urinary incontinence (leaking when coughing, sneezing, or exercising). Fifteen women will receive 8 weekly treatments and be followed for 3 months. …

This study tests whether using virtual reality (VR) during pelvic floor exercises helps women who leak urine after childbirth. Fifty women, ages 22-35, who had a vaginal delivery 3-6 months ago will be randomly assigned to standard training or VR-enhanced training. The goal is to…

This study tests whether adding blood flow restriction (using a cuff to partially reduce blood flow to the thighs) to standard pelvic floor muscle training can better reduce stress urinary incontinence in postmenopausal women. Sixty women with mild to moderate leakage will be spl…

This study tests whether adding a non-invasive electromagnetic chair treatment (HIFEM) to standard pelvic floor training can better reduce urine leakage in women aged 65-85 with daily stress incontinence. One hundred participants will be randomly assigned to either pelvic floor t…

This study looks at whether adding pelvic floor muscle training to vaginal estrogen therapy helps postmenopausal women with stress urinary incontinence more than estrogen alone. About 115 women will be randomly assigned to either the combined treatment or estrogen-only group. The…

This study will use millimeter-wave radar to measure how the pelvic floor muscles move in 2,000 women, both healthy and those with stress urinary incontinence. The goal is to create a large database of normal movement patterns and build a standard assessment system. This is an ob…

This study looks at whether reading a short educational flyer helps women learn more about stress urinary incontinence (SUI). About 90 adult women visiting a urogynecology clinic will fill out a quiz before and after reading the pamphlet. The goal is to see if the pamphlet improv…

This study will compare two different EMG methods (surface and intravaginal) and digital palpation to measure pelvic floor muscle strength in 24 women with stress urinary incontinence. The goal is to see if the methods give different results. This is an observational study, not a…

This study will look at 1,100 older women in Hong Kong, including 1,000 with urinary incontinence and 100 without, to better understand the condition. Researchers will explore how common different types of incontinence are, what traditional Chinese medicine patterns appear, and w…

This study will follow 200 women who are either taking GLP-1 weight loss drugs or undergoing bariatric surgery. Researchers want to see how these treatments change pelvic floor symptoms like incontinence and prolapse. Participants do not need to have any pelvic floor symptoms to …