New painkiller could replace opioids after pelvic surgery
NCT ID NCT07600697
First seen May 28, 2026 · Last updated Jun 23, 2026 · Updated 7 times
Summary
This study tests a drug called suzetrigine to see if it can control pain after transvaginal pelvic surgery without using strong opioids. About 120 women will receive either suzetrigine plus standard pain relievers or standard care with opioids. The goal is to see if suzetrigine works just as well while reducing opioid use and side effects.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, Los Angeles (UCLA)
Los Angeles, California, 90095, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Suzetrigine
What this could lead to
If it works, this could offer a non-opioid painkiller option for women recovering from pelvic surgery, reducing reliance on addictive opioids.
What could go wrong
This is a small, early-phase trial (120 people) testing non-inferiority, so suzetrigine may not control pain as well as opioids. It also requires scheduled acetaminophen and ibuprofen, so it's not a standalone solution.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.