Enamel caries
MONDO:0002233A dental caries that involves the enamel.
Also known as: dental caries limited to enamel, dental caries of enamel, enamel dental caries
79 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Could your own tooth help regrow jawbone? new trial tests graft and laser combo
Disease control ENROLLING_BY_INVITATIONThis study tests whether a graft made from a person's own extracted tooth, with or without low-level laser therapy, helps regrow jawbone after a tooth is pulled. About 21 healthy adults who need at least two back teeth removed and later replaced with implants will take part. The …
Phase: NA • Sponsor: Istanbul Saglik Bilimleri University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New peptide varnish could reverse white spots without drilling
Disease control ENROLLING_BY_INVITATIONThis study tests two different varnishes for treating white spot lesions, which are early signs of tooth decay common after braces. One varnish uses a self-assembling peptide to help rebuild enamel, while the other delivers calcium and phosphate. Thirty-eight people aged 15-25 wi…
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New varnish aims to stop root decay in seniors
Prevention OngoingThis study tests whether adding a special glass material to standard fluoride varnish can better prevent root cavities in adults over 60. Researchers will compare the two varnishes in 540 older adults over 36 months. The goal is to see which one reduces new cavities and helps sto…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Prevention
Last updated Jun 27, 2026 12:24 UTC
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New fluoride resin may stop tooth stains from clear aligners
Prevention OngoingThis study tests whether using a fluoride-releasing composite resin for aligner attachments can prevent white spot lesions (early cavities) during clear aligner therapy. Twenty-four people aged 16-24 with mild crowding will have one side of their mouth get the fluoride resin and …
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated Jun 27, 2026 09:08 UTC
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Fluoride varnish may shield teeth from white spots during aligner therapy
Prevention OngoingThis study tests whether applying fluoride varnish to teeth can prevent white spot lesions in people undergoing clear aligner treatment. Twenty-five participants aged 16 to 24 with mild crowding will have one side of their mouth treated with fluoride varnish and the other side le…
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated Jun 27, 2026 08:08 UTC
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Can a simple whitening gel erase white spots on teeth?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a 10% carbamide peroxide gel, used at home, can make white spot lesions on teeth less noticeable. About 67 adults with white spots on their front teeth will use the gel and report their satisfaction. The researchers will also check for side effects like t…
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Weekly Check-Ins could boost patient satisfaction for chronic pain
Knowledge-focused TerminatedThis study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can a special clinic get workers back on the job faster? norway launches massive study.
Knowledge-focused OngoingThis study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…
Phase: NA • Sponsor: Nordlandssykehuset HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Tongue-Side attachments may keep teeth Spot-Free during clear aligner treatment
Knowledge-focused OngoingWhite spot lesions are a common cosmetic problem during orthodontic treatment. This study tests whether placing the small composite attachments on the tongue side of clear aligners, instead of the front, reduces these spots. Fifty-two young adults with mild to moderate crowding a…
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Massive PT study mines 4 million records to find what works best
Knowledge-focused OngoingThis study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …
Sponsor: ATI Holdings, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Phone app vs. doctor: can a mobile tool catch infections after surgery?
Knowledge-focused TerminatedThis study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC