Enamel caries
MONDO:0002233A dental caries that involves the enamel.
Also known as: dental caries limited to enamel, dental caries of enamel, enamel dental caries
53 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Gum surgery breakthrough: new technique covers exposed roots in tough cases
Disease control CompletedThis completed study tested a surgical technique called the combined bilaminar tunnel method for treating gum recession in patients with challenging tooth anatomy. Twelve participants received the procedure and were followed for six months. The goal was to see how much of the exp…
Phase: NA • Sponsor: Choying Lin • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Ballet Dancers' teeth get a better fill: new ceramic outlasts standard composite
Disease control CompletedThis study tested two types of dental fillings for cavities and tooth wear at the gum line in 20 professional ballet dancers. One filling was a ceramic-like material (PICN) and the other was a self-hardening composite. Over 24 months, the ceramic fillings had zero failures, while…
Phase: NA • Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New tooth coating shows promise in reversing early cavities
Disease control CompletedThis study tested a product called DoReMin to see if it can help repair early tooth decay (white spot lesions). 43 adults with at least two early cavities on different teeth took part. One tooth was treated with DoReMin, while a similar tooth was left untreated for comparison. Re…
Phase: NA • Sponsor: Ivoclar Vivadent AG • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New filling material takes on standard for Gum-Line cavities
Disease control CompletedThis study tested two types of dental fillings for cavities that form near the gum line on front teeth. Fifty adults received either an alkasite-based resin composite or a resin modified glass ionomer filling. Dentists checked the fillings right away, at 6 months, and at 1 year t…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Toothpaste showdown: which paste wins the cavity war?
Disease control CompletedThis study tested three different toothpastes to see how well they prevent cavities. Thirty-six healthy adults wore a special dental device for six weeks, and researchers measured changes in enamel hardness. The goal was to find which toothpaste best protects teeth from decay.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New study tests which dental filling lasts longest
Disease control CompletedThis study tested four different tooth-colored filling materials for small cavities on the chewing surface of back teeth. Ten people received each type of filling, and researchers checked how well they held up over two years. The goal was to see which material performed best and …
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New tooth treatments battle ugly white spots without drilling
Disease control CompletedThis study tested two treatments for white spot lesions on teeth, which are common after braces. One uses a self-assembling peptide with fluoride to rebuild enamel, and the other uses a protective coating that releases minerals. Forty-four people with at least two white spots wer…
Phase: NA • Sponsor: Nahda University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can special toothpastes stop white spots from clear aligners?
Disease control CompletedThis study tested three different products (CPP-ACP, nano-hydroxyapatite, and fluoride varnish) against regular fluoride toothpaste to see which best prevents white spots on teeth near clear aligner attachments. Forty people completed the 6-month study. Researchers used a special…
Phase: NA • Sponsor: Bezmialem Vakif University • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New fluoride gel shows promise in reversing early cavities
Disease control CompletedThis study tested a new fluoride product to see if it can help remineralize white spot lesions—early signs of tooth decay. Twenty-three people with at least two active spots on their front teeth or premolars received both the experimental treatment and a standard fluoride varnish…
Phase: NA • Sponsor: Ivoclar Vivadent AG • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Can a glowing dye reveal hidden tooth decay?
Diagnosis CompletedThis study tests whether a special light-based scanner, called DIAGNOcam, can better detect early cavities between teeth when used with a dye. Researchers will compare this method to standard X-rays and a visual-tactile exam. The goal is to see if the dye improves the ability to …
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Diagnosis
Last updated Aug 09, 2026 00:00 UTC
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New Light-Based tools could catch cavities before they start
Diagnosis CompletedThis study tested four methods for finding early tooth decay in children aged 6 to 14. Researchers compared standard visual inspection with three special tools that use light or lasers. The goal was to see which method works best for spotting cavities that haven't yet formed a ho…
Sponsor: Neslihan Atmaca • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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Probiotic lozenges may stop Braces-Related tooth stains
Prevention CompletedThis study tested whether probiotic lozenges can prevent white spots (early cavities) that often appear around braces. 75 healthy people with braces took part. Some used probiotic lozenges, some used a control lozenge, and some had no extra treatment. The researchers measured new…
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Prevention
Last updated Jun 27, 2026 12:05 UTC
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At-Home dental cleanings may save Seniors' teeth
Prevention CompletedThis study tested whether having a dental assistant visit older adults at home every three months for professional cleaning and high-fluoride toothpaste could prevent root cavities. 194 home-living adults aged 65+ who needed daily care took part. The goal was to see if this appro…
Phase: NA • Sponsor: Karolinska Institutet • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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Tooth decay showdown: which treatment wins for white spots?
Symptom relief CompletedThis study tested two ways to treat early white spot lesions on teeth in 30 teenagers aged 12 to 18. Each participant received both a resin infiltration and a microabrasion treatment on different teeth to see which worked better. The goal was to improve the appearance and stop th…
Phase: NA • Sponsor: Can Tho University of Medicine and Pharmacy • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Pucker up! kissing may fight cavities, study finds
Knowledge-focused CompletedThis study looked at whether kissing can protect teeth from cavities. After drinking acidic beverages, one group kissed their partner for 40 seconds while a control group did not. Researchers measured saliva pH every 5 minutes to see if kissing helped neutralize acid faster. The …
Phase: NA • Sponsor: Universidad Catolica Santiago de Guayaquil • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Blood pressure pills linked to root cavities? new study investigates
Knowledge-focused CompletedThis study looked at 209 older adults (ages 50-70) taking blood pressure medication to see how many had cavities on the roots of their teeth. Researchers also checked saliva acidity and other risk factors. The goal was to understand if these medications are linked to root cavitie…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Braces and toothpaste: which one keeps your teeth whitest?
Knowledge-focused CompletedThis study looked at 45 people with braces to see if different toothpastes change tooth color or cause white spots. Participants used one of three toothpastes: Colgate Total, Curaprox, or ROCS. Researchers used 3D scans and special fluorescence photos to measure color changes ove…
Sponsor: Taner OZTURK, DDS, MS • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:01 UTC