New tooth treatments battle ugly white spots without drilling

NCT ID NCT07086235

Completed Disease control Sponsor: Nahda University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two treatments for white spot lesions on teeth, which are common after braces. One uses a self-assembling peptide with fluoride to rebuild enamel, and the other uses a protective coating that releases minerals. Forty-four people with at least two white spots were treated, and the researchers measured color change and lesion depth. The goal is to find a better, less invasive way to improve tooth appearance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: self-assembling peptide with fluoride (Curodont Repair Fluoride Plus) and tooth protective coating with surface pre-reacted glass (S-PRG Barrier Coat)
What this could lead to: If successful, this could offer a minimally invasive way to restore the natural appearance of teeth with white spots, improving patient satisfaction without drilling or anesthesia.
What could go wrong: This is a small, completed trial with only 44 participants, so results may not apply to everyone. The treatments are cosmetic and do not cure underlying decay or disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

enamel caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

WHITE SPOT LESIONS

Contacts and locations

Locations

Nahda University

Banī Suwayf, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.