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Silver-Coated braces aim to stop decay before it starts

NCT ID NCT07707336

Prevention Sponsor: Ajman University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether orthodontic brackets coated with silver nanoparticles can prevent enamel demineralization—the earliest stage of tooth decay—in people getting fixed braces. Sixteen participants scheduled for premolar extractions as part of their orthodontic treatment will receive both coated and standard brackets on different teeth. After one month, the extracted teeth are examined to compare enamel health around each bracket type.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Silver nanoparticle-coated stainless steel orthodontic brackets
What this could lead to
If effective, these brackets could offer a simple way to prevent white spots and early decay during orthodontic treatment, reducing the need for later fillings.
What could go wrong
This is a very small, early-stage study with only 16 participants and a short one-month follow-up. Results may not apply to all patients or predict long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Sep 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for fixed orthodontic treatment requiring premolar extraction * No history of previous orthodontic treatment done * Intact enamel surface of the premolars to be extracted Exclusion Criteria: * Non-extraction cases * Patients with previously done orthodontic treatment * Enamel surface defects on the premolars to be extracted(caries, hypoplasia, cracks etc.)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Enamel demineralization White spot lesions

Contacts and locations

Locations

  • Ajman University

    Ajman, United Arab Emirates

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