Battle of the white spot busters: paste vs. resin for Post-Braces cavities
NCT ID NCT05733676
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This trial compares two treatments for white spot lesions—early cavities that appear as milky-white marks on front teeth after braces. One treatment uses a special paste (MI Paste Plus) combined with etching, while the other uses a resin infiltration technique (Icon). The study involves 62 people aged 12–21 who have at least one white spot after orthodontic treatment. Researchers will track how well each treatment stops the lesion from progressing and improves its appearance over 18 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MI Paste Plus (casein phosphopeptide-amorphous calcium phosphate with fluoride) and resin infiltration (Icon)
What this could lead to
If one treatment proves clearly better, dentists may have a more effective, esthetic option to reverse early cavities after braces, reducing the need for fillings.
What could go wrong
This is a small, early-stage trial with only 62 participants. Results may not apply to everyone, and long-term effects beyond 18 months are not studied.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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KAYE Edmonton Clinic
RECRUITINGEdmonton, Alberta, T6G 1Z1, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••