Ehlers-Danlos syndrome
MONDO:0020066The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
Also known as: Danlos Disease, Ehlers, Danlos disease, Disease, Ehlers Danlos, Disease, Ehlers-Danlos, Dystrophia mesodermalis congenita, EDS, Ehler Danlos Syndrome, Ehlers Danlos Disease
43 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Pilates during pregnancy may speed up postpartum recovery
Disease control CompletedThis study tested whether a structured Pilates program during pregnancy, continued until childbirth, helps women recover ligament strength and reduce pain after giving birth. Researchers followed 42 women at 6 weeks postpartum, measuring joint looseness and activity limitations. …
Sponsor: Ankara Medipol University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
-
Could online pilates ease pain for those with stretchy joints?
Symptom relief CompletedThis study investigates whether an online Pilates program designed for people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder can reduce pain and improve function. Participants follow 25-minute guided videos three times a week for eight weeks. Researche…
Phase: NA • Sponsor: Clarkson University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
-
Ear stimulation device shows promise for Ehlers-Danlos relief
Symptom relief CompletedThis study tested whether a small, at-home device that stimulates a nerve in the ear can improve symptoms like pain, fatigue, sleep, and mood in people with hypermobile Ehlers-Danlos syndrome (hEDS). Twenty-five adults with hEDS used the device daily for two weeks, with some rece…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
-
Could a simple ear device ease hEDS symptoms?
Symptom relief CompletedThis study tested a wearable device that delivers mild electrical stimulation to the ear in 30 adults with hypermobile Ehlers-Danlos syndrome (hEDS). The goal was to see if it could improve quality of life by reducing symptoms like pain, fatigue, sleep problems, and anxiety. Part…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
-
Could tight clothing and dance help EDS patients regain balance?
Symptom relief CompletedThis study tested whether wearing compression garments and doing specific physiotherapy exercises could improve balance and quality of life in people with hypermobile Ehlers-Danlos syndrome (hEDS). Forty patients with hEDS were followed for a year, first receiving standard care, …
Phase: NA • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
-
New foot training shows promise for ankle sprain relief in athletes
Symptom relief CompletedThis study looked at whether a program called Hyperarch Fascia Training (HFT) can reduce ankle pain and improve jumping ability in active adults aged 20-45 who have had ankle sprains. 62 participants were split into two groups: one did HFT exercises remotely for 12 weeks, while t…
Phase: NA • Sponsor: Applied Science & Performance Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
-
Could a special vest ease crippling joint pain in Ehlers-Danlos patients?
Symptom relief CompletedThis study tested whether a custom compression vest (SED CICATREX®) can reduce shoulder pain and improve stability in adults with hypermobile Ehlers-Danlos syndrome. 48 participants wore the vest for 4 weeks, then went without it for 4 weeks. Researchers measured muscle strength,…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
-
Exercise eases shoulder fatigue in new study
Symptom relief CompletedThis study tested whether a supervised exercise program (MoveUS) could reduce fatigue and improve quality of life in 108 adults with shoulder instability. Participants were randomly assigned to either the exercise program or usual care. The results will help determine if this app…
Phase: NA • Sponsor: University of Malaga • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
-
Women's knee injury risk: new study probes hormone link
Knowledge-focused CompletedThis study looked at how hormones and birth control pills affect knee ligament looseness in healthy women. Researchers measured knee laxity in 45 women at two points in their menstrual cycle, comparing those on hormonal contraceptives to those not. The goal was to better understa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
-
Gene sequencing uncovers mysterious fetal malformations
Knowledge-focused CompletedThis study tested whether a powerful DNA test called high-throughput exome sequencing can find genetic causes of multiple birth defects in fetuses when standard exams fail. Researchers studied 100 fetuses with at least two malformations and no prior diagnosis. They compared the n…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
-
Speedy gene test aims to give answers on birth defects in just 7 days
Knowledge-focused CompletedThis study tested whether a fast type of genetic test called rapid genome sequencing can find the cause of birth defects seen on ultrasound more quickly than current methods. Researchers included 184 pregnancies with certain ultrasound findings. The goal was to see if results cou…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
-
Gene hunt for EDS: could saliva replace blood tests?
Knowledge-focused CompletedThis study collected blood and saliva from 334 people with Ehlers-Danlos syndrome and their relatives to find genetic differences linked to the condition. Researchers compared DNA from 30 patients and 30 relatives using advanced gene sequencing. The goal was to create a genetic t…
Sponsor: Boston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
-
Can flat feet or knock knees affect how kids move? new study investigates
Knowledge-focused CompletedThis completed study looked at 151 children with common postural conditions like flat feet, knock knees, or scoliosis. Researchers used wearable motion sensors and clinical tests to measure balance and motor control, then compared the results to healthy children. The goal was to …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC