Gene hunt for EDS: could saliva replace blood tests?

NCT ID NCT03093493

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collected blood and saliva from 334 people with Ehlers-Danlos syndrome and their relatives to find genetic differences linked to the condition. Researchers compared DNA from 30 patients and 30 relatives using advanced gene sequencing. The goal was to create a genetic test panel and see if saliva could be used instead of blood for easier testing. No treatment or results were given to participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a genetic test to help diagnose Ehlers-Danlos syndrome more easily.
What could go wrong
This is a small pilot study that only looks at genes, not a treatment. Results are not shared with participants, and it may not lead to a usable test.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

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Other studies related to the condition(s) this trial covers.