Dysmenorrhea
MONDO:1060205A menstrual disorder characterized by pain during the menstrual cycle.
92 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Breathing technique may offer Drug-Free relief for menstrual cramps
Symptom relief Not yet recruitingThis trial tests whether an 8-week program of coordinated breathing and pelvic floor exercises can reduce pain and improve quality of life in university women aged 18-24 with primary dysmenorrhea (painful periods without underlying disease). Participants will either do the exerci…
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Hands-On therapy may ease period pain and improve C-Section scar mobility
Symptom relief Not yet recruitingThis trial investigates whether adding a hands-on technique called abdominopelvic fascial release to stretching exercises can reduce menstrual pain and improve scar mobility in women who have had a cesarean section. The study enrolls women aged 20 to 35 with moderate to severe pe…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Pilates or gym: which eases period pain best?
Symptom relief Not yet recruitingThis study tests whether Pilates or gym exercises better relieve pain from primary dysmenorrhea (period pain) in young women aged 17-25. Fifty-two participants will do either Pilates or gym workouts three times a week for three months. Researchers will measure pain intensity, sym…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Tapping away period pain: emotional freedom techniques put to the test
Symptom relief Not yet recruitingThis study tests whether Emotional Freedom Techniques (EFT), a therapy that combines tapping on acupressure points with focused thoughts, can reduce pain intensity, pain-related worrying, and emotional distress in nursing students who suffer from painful periods. Participants are…
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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New wearable sleeve aims to zap period pain without pills
Symptom relief Not yet recruitingThis study tests a wearable sleeve with semiconductors that claim to boost blood flow and reduce pain. One hundred women with painful periods will wear either the active sleeve or a placebo version. The goal is to see if the sleeve can ease cramping and improve quality of life wi…
Phase: NA • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Belly massage may soothe period pain, new study hopes to prove
Symptom relief Not yet recruitingThis study tests whether gentle belly massage can reduce period pain and improve quality of life in women with painful periods, with or without endometriosis. About 80 women will be randomly assigned to receive either real massage or a light touch (sham) over three menstrual cycl…
Phase: NA • Sponsor: Vrije Universiteit Brussel • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Talking therapy may ease period pain in teens
Symptom relief Not yet recruitingThis study tests a psychological program for teens aged 15-19 with painful periods. The program uses cognitive restructuring and psychoeducation to help them change negative thoughts and improve emotional control. Researchers will measure pain and coping skills before and after t…
Phase: NA • Sponsor: Universidad Autonoma de Baja California • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Exercise at home may be the new painkiller for period cramps
Symptom relief Not yet recruitingThis study tests whether an 8-week home exercise program can reduce pain and improve walking and brain function in young women with painful periods. Eighty-six single women aged 18-25 with moderate to severe period pain will do 30-minute sessions three times a week, including rel…
Phase: NA • Sponsor: University of Sharjah • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New supplement aims to soothe menstrual cramps without drugs
Symptom relief Not yet recruitingThis study tests whether a dietary supplement called CL25216 can help women with painful periods (primary dysmenorrhea). Eighty healthy women aged 25-40 will take either CL25216 or a placebo daily for 84 days. Researchers will measure changes in menstrual pain, pain duration, and…
Phase: NA • Sponsor: ApexCPG LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Could a vaginal pill ease severe period cramps?
Symptom relief Not yet recruitingThis early-stage trial tests whether a single vaginal dose of sildenafil (100 mg) can reduce painful uterine contractions during menstruation. About 50 adults with moderate-to-severe period pain will receive the drug or a placebo in two separate cycles. The study uses MRI to meas…
Phase: PHASE1 • Sponsor: Kevin Hellman • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Period app trial aims to ease teen menstrual misery
Symptom relief Not yet recruitingThis study tests whether a mobile app that tracks periods and teaches about menstrual health can improve quality of life for teens with painful or heavy periods. About 874 adolescents who have started their periods and speak Dutch, English, Turkish, or Moroccan-Arabic will use th…
Phase: NA • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Mindfulness may soothe period pain without pills
Symptom relief Not yet recruitingThis study tests whether an 8-session mindfulness-based compassionate living program can help university students with painful periods feel less stress, less pain, and more in control. About 68 students will either take the training or receive no intervention. Researchers will me…
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Can learning about comfort reduce period cramps? new study investigates
Symptom relief Not yet recruitingThis study tests whether a comfort theory-based education program can help university students with primary dysmenorrhea (painful periods) feel better. The program involves three face-to-face sessions over three months, each lasting 40 minutes. Researchers will compare pain level…
Phase: NA • Sponsor: Ordu University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Shocking period pain away? new trial tests nerve zap for cramps
Symptom relief Not yet recruitingThis study tests whether a device that sends mild electrical pulses to a nerve in the ankle (TTNS) can reduce pain and distress from period cramps. Thirty-six women with primary dysmenorrhea will receive either standard care (heat packs and stretches) or standard care plus TTNS f…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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No pills, just pressure: self-massage study targets menstrual cramps
Symptom relief Not yet recruitingThis study tests whether a daily 5-20 minute abdominal self-massage can reduce menstrual pain. 46 female students in Germany will track their pain and medication use via a smartphone app over up to 60 days. Each person acts as their own control, comparing massage days to no-massa…
Phase: NA • Sponsor: University of Potsdam • Aim: Symptom relief
Last updated Jun 26, 2026 13:47 UTC
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Could a stiff c-section scar worsen period pain? scientists test the link
Knowledge-focused Not yet recruitingThis study looks at whether the mobility of a cesarean scar is related to the severity of menstrual pain in women who have had a C-section. Researchers will measure scar mobility, pain levels, and pressure sensitivity in 34 women aged 20–35 with regular cycles and period pain. Th…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Menstrual cramps may alter pelvic alignment, new study investigates
Knowledge-focused Not yet recruitingThis study looks at whether primary dysmenorrhea (painful periods) is linked to changes in the biomechanics of the lower back and pelvis. Researchers will compare female university students aged 18-24 who have moderate to severe menstrual pain with those who have little or no pai…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Period pain plagues med students: new study to measure toll on grades and life
Knowledge-focused Not yet recruitingThis study will survey 402 female medical students at Sohag University to understand how period pain (primary dysmenorrhea) impacts their academic performance and quality of life. Participants will fill out two questionnaires about their pain and its effects. The goal is to gathe…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Period pain study aims to uncover hidden health impacts
Knowledge-focused Not yet recruitingThis study will compare 70 women with and without primary dysmenorrhea (painful periods) to see how the condition affects pain sensitivity, joint flexibility, physical activity, breathing strength, attitudes about menstruation, and mood. Researchers hope to identify key areas aff…
Phase: NA • Sponsor: Izmir Democracy University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC