Could a vaginal pill ease severe period cramps?
NCT ID NCT07508358
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether a single vaginal dose of sildenafil (100 mg) can reduce painful uterine contractions during menstruation. About 50 adults with moderate-to-severe period pain will receive the drug or a placebo in two separate cycles. The study uses MRI to measure contractions and tracks pain relief over 4 hours.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DYSMENORRHEA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Evanston Hospital
Evanston, Illinois, 60201, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Building a biological treasure trove to decode Women's health mysteries
- Breathing technique may offer Drug-Free relief for menstrual cramps
- Could a stiff c-section scar worsen period pain? scientists test the link
- A soak for relief: testing magnesium footbaths against menstrual cramps
- Hands-On therapy may ease period pain and improve C-Section scar mobility
- Ear nerve stimulation may soothe period pain and mood