Dentin caries

This study tests whether one or two applications of 38% silver fluoride can stop cavities in the baby teeth of children aged 4 to 6 years. Researchers compare a single treatment against two treatments given three months apart, and also measure how the children's oral health affec…

This study tests whether a robot can place dental implants more accurately than a computer-guided navigation system in the front upper jaw. Twenty-four adults needing an implant will be randomly assigned to one of the two methods. The main goal is to see which approach achieves b…

This study tests a new material made from treated dentin and calcium silicate for treating deep cavities that have reached the tooth's nerve. The goal is to see if it can keep the nerve healthy better than the current standard material. Fifty-six people aged 14 to 35 with deep ca…

This study tests a new material called NeoPutty MTA against a standard chemical, formocresol, for treating deep cavities in children's back baby teeth. About 68 kids aged 4 to 9 will get one of the two treatments to save the tooth and prevent pain or infection. Researchers will c…

This study tests two cavity-stopping liquids in 60 children aged 3-5 with active tooth decay. One is a well-known treatment that turns cavities black; the other is a newer version that may avoid staining. Researchers will check which works better over 12 months, and ask parents a…

This study tests whether a new bioactive filling material helps teeth repair themselves after deep cavities are removed. 66 adults with deep decay will get either the bioactive filling or a standard one. Researchers will check for new tooth layer formation and pain over 2 years.

This study compares two dental treatments for teeth with deep cavities and reversible pulpitis (early nerve inflammation). One treatment caps the exposed nerve directly, while the other removes a small part of the nerve before capping. The study will include 138 people aged 15-40…

This study compares two cavity removal methods in 144 adults with deep cavities and reversible pulpitis (tooth nerve inflammation that can heal). One method removes all decay, the other leaves some near the nerve. Researchers will check pain, tooth vitality, and X-rays over 12 mo…

This study tests a handheld scanner that uses safe near-infrared light to find early cavities without radiation. Fifty adults scheduled for a tooth extraction will get an extra 5-minute scan before their procedure. The scanner's results will be compared to standard X-rays and vis…

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…

This study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…

This study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…

This study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …

This study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…