Dentin caries
MONDO:0001041A dental caries that involves the dentine.
Also known as: dental caries extending into dentine, dental caries of dentine, dentine dental caries
45 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Can leaving some decay save the tooth? a trial tests two gentle approaches
Disease control OngoingThis study compares two conservative methods for treating deep tooth decay that reaches close to the nerve. In one approach, dentists leave softer decayed tissue near the nerve; in the other, they remove more until firmer tissue remains. About 100 patients with deep decay in perm…
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
-
Less drilling, same tooth saving? new trial tests gentler cavity care for teens
Disease control ENROLLING_BY_INVITATIONThis study compares two ways to treat deep cavities in young permanent teeth without exposing the nerve. In selective excavation, the dentist removes only the outer decay and seals the tooth. In stepwise excavation, they place a temporary filling first and remove more decay a few…
Phase: NA • Sponsor: Karolinska Institutet • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
-
Can a simple dental procedure save teeth from root canals?
Disease control OngoingThis trial compares two dental procedures—direct pulp capping and partial pulpotomy—for treating permanent teeth with deep cavities that expose the pulp. Adults with deep caries and reversible pulpitis will be randomly assigned to one of the two procedures. The study will follow …
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
-
A simple marker might predict which teeth can be saved without root canal
Disease control OngoingThis study tests whether the level of a specific inflammatory marker (MMP9) in the dental pulp can predict the success of a full pulpotomy, a procedure that removes the inflamed pulp from the crown of a tooth and seals it with a special material. Adults with deep cavities causing…
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
-
New filling material could save Kids' teeth from repeat dental work
Disease control OngoingThis study tests a special tooth-colored filling called alkasite composite (Cention Forte) for baby molars that have had pulp treatment. Twenty-five healthy children with deep cavities received this filling. Researchers are checking how well the fillings hold up over time using s…
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
-
Laser before filling may save more tooth in deep cavities
Disease control OngoingThis study tests whether using a diode laser before placing a special filling material (Biodentine) helps preserve more healthy tooth and reduces staining compared to using Biodentine alone. 48 adults with deep cavities in permanent back teeth are being treated and followed with …
Phase: NA • Sponsor: Misr International University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
-
Amniotic membrane could help Kids' teeth grow back stronger
Disease control OngoingThis study tests three materials—amniotic membrane, mineral trioxide aggregate putty, and biodentine—for treating deep cavities in children's permanent molars that are still growing. The goal is to help the tooth root finish developing and avoid root canal or extraction. Seventy-…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
-
VR game takes the fear out of Kids' first dental visit
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a virtual reality (VR) game can lower anxiety and pain in children aged 6 to 10 during their first dental treatment. Half of the 88 kids will wear VR glasses showing an interactive game that explains each step, while the other half gets the standard 'tell…
Phase: NA • Sponsor: Ankara University • Aim: Symptom relief
Last updated Jun 26, 2026 16:00 UTC