Amniotic membrane could help Kids' teeth grow back stronger

NCT ID NCT07336498

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests three materials—amniotic membrane, mineral trioxide aggregate putty, and biodentine—for treating deep cavities in children's permanent molars that are still growing. The goal is to help the tooth root finish developing and avoid root canal or extraction. Seventy-five healthy children aged 7 to 10 will receive one of the treatments, and their teeth will be checked for pain, swelling, and root growth using 3D X-rays over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
amniotic membrane, putty mineral trioxide aggregate, and biodentine
What this could lead to
If successful, this could provide a better way to treat damaged immature teeth in children, helping them grow normally and avoid extraction.
What could go wrong
This is a small, early-stage trial with only 75 participants. Results may not apply to all children, and the treatments may not work as hoped.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Al-Azhar University, Cairo (Boys Branch)

    Cairo, Egypt