New dental material could save more teeth from root canals

NCT ID NCT07302438

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new material made from treated dentin and calcium silicate for treating deep cavities that have reached the tooth's nerve. The goal is to see if it can keep the nerve healthy better than the current standard material. Fifty-six people aged 14 to 35 with deep cavities and reversible pulpitis will be randomly assigned to receive either the new material or the standard one during a miniature pulpotomy. Success will be measured by nerve response to cold and other signs of healing over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Calcium silicate-doped treated dentin matrix

What this could lead to

If it works, this could provide a better material for preserving tooth nerve health after deep cavity treatment, reducing the need for more invasive procedures.

What could go wrong

This is a small, early-stage trial with only 56 participants, so results may not apply broadly. The new material may not perform better than the standard treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dental caries dentin caries pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AIIMS Nagpur

    Nagpur, Maharashtra, 441108, India

  • AIIMS Nagpur

    Nagpur, Maharashtra, 441108, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••