Delusional disorder
MONDO:0004359A disorder characterized by the presence of one or more nonbizarre delusions that persist for at least 1 month; the delusion(s) are not due to schizophrenia or a mood disorder, and do not impair psychosocial functioning apart from the ramifications of the delusion(s).
73 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Drugs and therapy together: a new hope for anxiety, depression, and more?
Disease control CompletedThis early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…
Phase: PHASE1 • Sponsor: Rakitzi, Stavroula • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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New behavioral program aims to keep people with mental illness out of jail
Disease control CompletedThis study tests a new group program called Forging New Paths for adults with serious mental illness who have also been involved with the criminal justice system. The program combines cognitive behavioral therapy with social learning techniques to reduce aggression and help peopl…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Can two antipsychotics together tame schizophrenia better?
Disease control CompletedThis study looked at 6 people with schizophrenia who were already taking a combination of two long-acting injectable medications: Abilify Maintena and Rexulti. Researchers tracked their symptoms and side effects over 6 months to see how well the combo worked in everyday life. The…
Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Can a brief chat help young people with psychosis cut back on pot?
Disease control CompletedThis pilot study tested a counseling program called the Teen Marijuana Check Up, adapted for young adults (ages 13–35) who have early psychosis and use cannabis. The program uses motivational interviewing and personalized feedback over two sessions to help participants reduce or …
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 26, 2026 13:46 UTC
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Mindfulness may keep psychosis at bay
Prevention CompletedThis study tested whether mindfulness training can prevent relapse in people with psychosis. 152 participants who were in remission were randomly assigned to either mindfulness training or standard education. Researchers tracked them for 12 months to see who had a relapse.
Phase: NA • Sponsor: The University of Hong Kong • Aim: Prevention
Last updated Jun 27, 2026 12:34 UTC
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Can virtual reality help quiet paranoia in schizophrenia?
Symptom relief CompletedThis trial tests whether adding virtual reality to cognitive behavioural therapy (CBT) can better reduce persecutory thoughts in people with schizophrenia spectrum disorders compared to traditional CBT alone. About 256 participants will receive either VR-assisted CBT or standard …
Phase: NA • Sponsor: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital • Aim: Symptom relief
Last updated Aug 14, 2026 00:00 UTC
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Two-Session therapy boosts engagement in youth with psychosis
Symptom relief CompletedThis study tested a brief, two-session therapy program for young adults (ages 18-35) who had recently started early psychosis services. The program, adapted from a US-based intervention called 'Just Do You,' aimed to improve treatment engagement and recovery by addressing barrier…
Phase: NA • Sponsor: Nova Scotia Health Authority • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Brain zaps show promise for silencing hallucinations
Symptom relief CompletedThis study tested whether a non-invasive brain stimulation technique called tDCS can reduce auditory hallucinations in people with psychotic disorders. Twenty-four participants received the stimulation while researchers measured changes in hallucination severity and brain activit…
Phase: NA • Sponsor: University of Bergen • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Gym workouts boost recovery in young adults on antipsychotics
Symptom relief CompletedThis study tested whether a 4-month gym exercise program helps young adults (18-35) taking antipsychotic medication for psychosis or mood disorders feel better in their daily lives. 226 participants were randomly assigned to either continue their usual care or add gym workouts. R…
Phase: NA • Sponsor: Rigshospitalet, Denmark • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Art as medicine: study tests whether theatre, dance, and music ease depression
Symptom relief CompletedThis study tested whether taking part in art activities like theatre, dance, visual arts, music, or cinema can improve mental health. 541 adults with psychiatric diagnoses were randomly assigned to either an art program or a waitlist. Researchers measured changes in depression an…
Phase: NA • Sponsor: KAVADIA ELENI • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Nature walks may ease psychosis symptoms, small study hints
Symptom relief CompletedThis study tested whether forest therapy—mindful walking, sun bathing, hugging trees, and meditation—could improve symptoms and reduce inflammation in 80 adults with psychotic disorders. Half received forest therapy plus standard care for 8 weekly sessions; the other half receive…
Phase: NA • Sponsor: Natalia Dewi Wardani, MD • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Can a smartphone app help young people with psychosis cut back on cannabis?
Symptom relief CompletedThis pilot study tested a mobile app called iCanChange in 100 young adults (ages 18-35) with psychosis and cannabis use disorder. The app uses motivational interviewing and cognitive behavioral therapy techniques through short interactive modules. The main goal was to see if the …
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Smartphone apps show promise for schizophrenia symptom management
Symptom relief CompletedThis study tested two mobile health (mHealth) strategies to help people with schizophrenia manage their symptoms. 299 participants used smartphone tools to track and improve issues like depression, anxiety, and insomnia. The goal was to see if these digital tools could make a rea…
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Could VR help sharpen your mind? new study tests brain training in virtual reality
Symptom relief CompletedThis study tested whether a 4-week virtual reality (VR) training program could improve thinking skills in 62 people with depression, bipolar disorder, or psychotic disorders like schizophrenia. Participants practiced daily-life tasks in VR, such as cooking and shopping, guided by…
Phase: NA • Sponsor: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Can social training help veterans with psychosis connect better?
Symptom relief CompletedThis study tested two different 2-month training programs to help veterans with psychosis improve their social interactions and quality of life. 113 veterans took part. The goal was to see which training worked better for everyday social situations.
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Zapping the brain to silence hallucinations: small study shows promise
Symptom relief CompletedThis completed study tested whether a mild electrical current applied to a specific brain region (the right superior temporal sulcus) could reduce hallucinations in 12 adults with psychosis. Participants received transcranial electrical stimulation while researchers measured chan…
Phase: NA • Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Jun 26, 2026 17:58 UTC
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Impostor syndrome among Athlete-Scholars: can sleep and social media play a role?
Knowledge-focused CompletedThis study surveys Indonesian sports science undergraduates to understand how self-esteem, anxiety, sleep habits, and social media use relate to feelings of being a fraud (impostor phenomenon). Researchers aim to identify which psychological, behavioral, and structural factors mo…
Sponsor: Hasanuddin University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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New pilot study aims to help people with psychosis in africa through peer support and community resources
Knowledge-focused CompletedThis pilot study tested a community-based intervention for people with psychosis in Malawi, Nigeria, Sierra Leone, and Zimbabwe. The program includes peer support from someone who has experienced psychosis, case management, and help with daily activities like finding work or soci…
Phase: NA • Sponsor: London School of Hygiene and Tropical Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Uganda study lets people with psychosis help shape their own care
Knowledge-focused CompletedThis study tested a new way to improve mental health services for people with psychosis in Uganda. Instead of just doctors making decisions, people who have experienced psychosis were trained to help at home, in the community, and at clinics. The goal was to see if this approach …
Phase: NA • Sponsor: George Washington University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Texting teens with psychosis: a simple nudge to get them to care
Knowledge-focused CompletedThis study tested whether sending text message reminders and support to young people with psychosis after an emergency room visit helps them attend their first early psychosis appointment. 186 participants were enrolled. The goal was to see if a low-cost, youth-friendly approach …
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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AI coach for therapists: could a digital tool improve psychosis care?
Knowledge-focused CompletedThis study tested a new digital tool called CBTpro that uses artificial intelligence to help therapists improve their skills in cognitive behavioral therapy for psychosis (CBTp). Over 600 participants, including therapists and their clients with conditions like schizophrenia or b…
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can video therapy help families cope with psychosis and addiction?
Knowledge-focused CompletedThis study tested a program called CRAFT-EP, which helps families support a relative with early psychosis and substance use (like alcohol or cannabis). The program was delivered entirely through video calls. Researchers measured family members' depression and anxiety to see if th…
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Brain wave test may personalize thinking skills training for veterans
Knowledge-focused CompletedThis study tested whether a brain wave measurement called mismatch negativity (MMN) can help match veterans with mental illness to the most effective cognitive training program. 100 veterans with conditions like schizophrenia, PTSD, or mood disorders participated. The goal was to…
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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New training aims to give veterans with mental illness a stronger voice in their care
Knowledge-focused CompletedThis study tested a program called Collaborative Decision Skills Training (CDST) to help veterans with serious mental illness (like schizophrenia or major depression with psychosis) work more closely with their doctors in making treatment decisions. The program involved eight wee…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Could nurse home visits help psychosis patients in malawi?
Knowledge-focused CompletedThis pilot study tested whether a nurse-led community-based rehabilitation program is feasible and acceptable for people with psychosis in Blantyre, Malawi. Sixty adults with psychosis were randomly assigned to either usual care or the home-based program. The study focused on rec…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New police hotline aims to keep mentally ill out of jail
Knowledge-focused CompletedThis study tested a system where police officers can call a mental health provider during encounters with people who have serious mental illness. The goal was to see if this reduces arrests and helps people stay connected to care. Over 1,400 participants were randomly assigned to…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:39 UTC
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Could Low-Nicotine smokes plus E-Cigs cut harm for mentally ill smokers?
Knowledge-focused CompletedThis study looked at whether using very low nicotine cigarettes along with nicotine-containing e-cigarettes can reduce harmful chemical exposure in smokers with mental health conditions. 88 participants were assigned to different combinations of cigarettes and e-cigarettes. The m…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:59 UTC