Cleft lip and alveolus
MONDO:0015420Cleft lip and alveolus is a fissure type embryopathy that involves the upper lip, nasal base and alveolar ridge in variable degrees.
51 clinical trials for this condition and its sub-types.
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Broader categories
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New device shrinks jaw gaps in cleft patients, boosts graft success
Disease control CompletedThis study tested a new, simple device to reduce the size of wide gaps in the jawbone (alveolar clefts) in 15 people aged 12-25 with repaired cleft lip and/or palate. The device slowly pulls the bone together before a bone graft, aiming to make the graft more successful. The stud…
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New putty could replace painful bone grafts for kids with cleft palate
Disease control CompletedThis study tested a new calcium phosphate putty to repair bone gaps in the gums of 84 children with unilateral cleft lip and palate. The putty was compared to the standard approach of using the child's own bone. Researchers measured how much bone remained after one year, as well …
Phase: NA • Sponsor: UMC Utrecht • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Sticky bone graft shows promise for fixing cleft defects
Disease control CompletedThis study tested a new method to repair a type of cleft palate that affects the upper gum (unilateral alveolar cleft). Ten patients received a 'sticky bone' graft combined with a special growth factor membrane. The researchers checked for inflammation, fluid leaking into the nos…
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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New device aims to close wide gum clefts without bone grafts
Disease control CompletedThis study tested a special device placed inside the mouth to slowly pull bone across a wide gap in the gum (alveolar cleft) in 8 patients aged 7 to 20. The goal was to close the gap without needing a bone graft. Researchers measured changes in the cleft size, tooth movement, and…
Phase: NA • Sponsor: Faculty of Dental Medicine for Girls • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New bone graft method shows promise for kids with cleft palate
Disease control CompletedThis study tested two different bone graft materials to repair a common birth defect called alveolar cleft (a gap in the upper jaw). Fourteen children aged 8 to 12 received either a standard graft or one mixed with a special blood product. The goal was to see which material led t…
Phase: NA • Sponsor: Beni-Suef University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New scale could help predict fall risk for hospital patients in turkey
Diagnosis CompletedThis study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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Physiotherapy students test muscle relief techniques on themselves
Symptom relief CompletedThis study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Jaw implants aim to boost life quality after surgery
Symptom relief CompletedThis study looked at how well Global D implants work for orthognathic (jaw) surgery and whether they improve patients' quality of life. 198 people who had their first jaw surgery received these implants. Researchers measured quality of life before and after surgery using a specia…
Sponsor: Global D • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Who should control your sedation during surgery? new study compares options
Symptom relief CompletedThis study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New turkish health survey could improve care for muscle and joint problems
Knowledge-focused CompletedThis study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…
Sponsor: Istanbul Bilgi University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Physios take on ER duty: study tests if they can replace doctors for back pain
Knowledge-focused CompletedThis study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Mind, spirit, and pain: new study explores what chronic pain patients really believe
Knowledge-focused CompletedThis study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Nerve blocks may cut opioid use in newborn cleft lip repair
Knowledge-focused CompletedThis completed study looked at 111 newborns who had cleft lip repair surgery. Researchers compared those who received a regional nerve block for pain relief to those who did not. The goal was to see if the nerve block reduced the amount of opioid pain medicine needed during and a…
Sponsor: Brno University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:22 UTC