Nerve blocks may cut opioid use in newborn cleft lip repair

NCT ID NCT06067854

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study looked at 111 newborns who had cleft lip repair surgery. Researchers compared those who received a regional nerve block for pain relief to those who did not. The goal was to see if the nerve block reduced the amount of opioid pain medicine needed during and after surgery. The study also checked for complications and how soon babies could eat after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If the nerve block reduces opioid use, it could point to safer pain management for newborns after cleft lip repair.

What could go wrong

This is a small, retrospective study, so it can't prove cause and effect. Results may not apply to all newborns or other surgeries.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cleft lip cleft lip and alveolus cleft lip/palate

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brno University Hospital

    Brno, South Moravian, 62500, Czechia