Cleft lip and alveolus
MONDO:0015420Cleft lip and alveolus is a fissure type embryopathy that involves the upper lip, nasal base and alveolar ridge in variable degrees.
17 clinical trials for this condition and its sub-types.
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Broader categories
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Jaw vs. hip bone: which graft works best for cleft repair?
Disease control Not yet recruitingThis study compares two surgical techniques to repair a bone gap in the upper jaw (alveolar cleft) in 20 people who missed earlier treatment. One method uses bone from the patient's jaw, the other from the hip. Researchers will measure bone volume and shape after 6 months to see …
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Could a diabetes drug strengthen bone repair in kids with cleft palate?
Disease control Not yet recruitingThis study tests whether adding metformin gel to a standard bone graft improves bone quality in children aged 8 to 12 with a cleft in the upper jaw (alveolar cleft). 36 participants will be randomly assigned to receive either the metformin-enhanced graft or a placebo. The main go…
Phase: PHASE2 • Sponsor: Fayoum University • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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New study tests better bone grafts for cleft palate patients
Disease control Not yet recruitingThis study compares two surgical techniques for repairing bilateral alveolar clefts (gaps in the upper jaw) using bone grafts from the hip. Twenty participants will receive either a solid bone block or loose bone chips. The goal is to see which method provides better bone volume …
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Cheek flap may boost bone growth in cleft repair
Knowledge-focused Not yet recruitingThis study looks at whether using a flap from the cheek (FAMM flap) helps bone grow better when repairing a cleft in the gum area. Five people aged 9 to 20 who already had braces to widen the palate will be included. Researchers will use 3D X-rays to measure bone height, width, a…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC