Cleft lip and alveolus

This study compares two surgical techniques to repair a bone gap in the upper jaw (alveolar cleft) in 20 people who missed earlier treatment. One method uses bone from the patient's jaw, the other from the hip. Researchers will measure bone volume and shape after 6 months to see …

This study tests whether adding metformin gel to a standard bone graft improves bone quality in children aged 8 to 12 with a cleft in the upper jaw (alveolar cleft). 36 participants will be randomly assigned to receive either the metformin-enhanced graft or a placebo. The main go…

This study compares two surgical techniques for repairing bilateral alveolar clefts (gaps in the upper jaw) using bone grafts from the hip. Twenty participants will receive either a solid bone block or loose bone chips. The goal is to see which method provides better bone volume …

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…

This study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…

This study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…

This study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …

This study looks at whether using a flap from the cheek (FAMM flap) helps bone grow better when repairing a cleft in the gum area. Five people aged 9 to 20 who already had braces to widen the palate will be included. Researchers will use 3D X-rays to measure bone height, width, a…

This study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…