Could a diabetes drug strengthen bone repair in kids with cleft palate?

NCT ID NCT07536620

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding metformin gel to a standard bone graft improves bone quality in children aged 8 to 12 with a cleft in the upper jaw (alveolar cleft). 36 participants will be randomly assigned to receive either the metformin-enhanced graft or a placebo. The main goal is to measure bone density using a special CT scan.

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Conditions

The condition(s) this trial relates to.

cleft lip and alveolus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.