Chemotherapy-induced oral mucositis
MONDO:0005588Inflammation and ulceration of the oral mucosa as a result of chemotherapy treatment.
26 clinical trials for this condition and its sub-types.
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Can a simple mouthwash tame the painful side effects of radiation?
Disease control CompletedThis trial tests two different mouthwashes—benzydamine hydrochloride and super saturated calcium phosphate—to see which better prevents and manages oral mucositis, a painful inflammation of the mouth lining, in head and neck cancer patients receiving radiation therapy. Participan…
Phase: NA • Sponsor: Postgraduate Medical Institute, Lahore • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Could a laser beam stop chemo mouth sores?
Prevention CompletedThis trial investigates whether a low-level diode laser can prevent or reduce severe mouth sores (mucositis) caused by radiation and chemotherapy in people with advanced head and neck cancer. Participants receive either real laser therapy or a non-functional placebo laser during …
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Prevention
Last updated Jul 03, 2026 00:00 UTC
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Ozone may soothe cancer Patients' painful mouth sores
Symptom relief CompletedThis study looked back at medical records of 58 adult cancer patients who developed painful mouth sores from chemotherapy or radiation. They had been treated with a combination of ozone applied in the dentist's chair and ozone-based gels, toothpaste, and mouthwash at home. The go…
Sponsor: University of Pavia • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Mouth spray may soothe painful sores from cancer radiation
Symptom relief CompletedThis study tested whether a benzydamine hydrochloride (Difflam) oral spray can reduce the severity of mouth sores caused by high-dose radiation in head and neck cancer patients. Thirty-five adults receiving radiation without chemotherapy were randomly assigned to standard mouth c…
Phase: PHASE4 • Sponsor: Tishreen University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Can arginine and glutamine soothe radiation mouth pain?
Symptom relief CompletedThis study tested whether mouth rinses containing the amino acids arginine or glutamine could reduce the severity of painful mouth sores caused by radiation therapy in head and neck cancer patients. 69 participants swished and swallowed these supplements three times daily during …
Phase: PHASE2 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New nursing protocol eases mouth pain for cancer patients
Symptom relief CompletedThis study aimed to create a better nursing plan for mouth sores caused by cancer treatments like chemo and radiation. Researchers worked with 54 cancer patients to test a new care routine based on the best available evidence. The goal was to reduce mouth soreness and improve dai…
Phase: NA • Sponsor: Peking Union Medical College • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Ozone treatment eases mouth pain for head and neck cancer patients
Symptom relief CompletedThis study tested ozone therapy to treat painful mouth sores caused by radiation and chemotherapy in 58 head and neck cancer patients. Patients received professional ozone treatments at the dental clinic plus ozone-based toothpaste, mouthrinse, and gel to use at home for 15 days.…
Phase: NA • Sponsor: University of Pavia • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC