Ozone may soothe cancer Patients' painful mouth sores
NCT ID NCT07638904
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked back at medical records of 58 adult cancer patients who developed painful mouth sores from chemotherapy or radiation. They had been treated with a combination of ozone applied in the dentist's chair and ozone-based gels, toothpaste, and mouthwash at home. The goal was to see how quickly the sores healed and whether pain improved. Because this was a small review of past cases with no comparison group, the findings are only hints, not proof.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ozone therapy (chairside ozone application and ozonized oral care products)
- What this could lead to
- If results are positive, this could point toward a simple, non-drug option to ease painful mouth sores during cancer therapy.
- What could go wrong
- This is a small, retrospective study with no control group, so results are only suggestive. It cannot prove ozone therapy works better than standard care or no treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CANCER THERAPY-RELATED ORAL MUCOSITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, 27100, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Olive oil and xylitol mouth rinse may shield cancer patients from painful mouth sores
- Can laser or ozone therapy better soothe cancer-related mouth pain? a head-to-head comparison
- Plant pigment could soothe Radiation's harsh side effect in blood cancer treatment
- Could a laser beam stop chemo mouth sores?
- New drug aims to spare cancer patients from debilitating mouth sores
- New lozenge aims to ease radiation mouth sores for hours