Ozone may soothe cancer Patients' painful mouth sores

NCT ID NCT07638904

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked back at medical records of 58 adult cancer patients who developed painful mouth sores from chemotherapy or radiation. They had been treated with a combination of ozone applied in the dentist's chair and ozone-based gels, toothpaste, and mouthwash at home. The goal was to see how quickly the sores healed and whether pain improved. Because this was a small review of past cases with no comparison group, the findings are only hints, not proof.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ozone therapy (chairside ozone application and ozonized oral care products)

What this could lead to

If results are positive, this could point toward a simple, non-drug option to ease painful mouth sores during cancer therapy.

What could go wrong

This is a small, retrospective study with no control group, so results are only suggestive. It cannot prove ozone therapy works better than standard care or no treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis stomatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia

    Pavia, Lombardy, 27100, Italy