Binge eating disorder

This study tests whether intensive home-based psychiatric treatment can help children and teens with mental health disorders as an alternative to being in the hospital. Over 3 months, participants receive 3 to 7 home visits per week from a team of doctors, therapists, and other s…

This study tests whether a combination of medication (naltrexone/bupropion, also known as Contrave) and behavioral weight-loss counseling can help people who experience loss-of-control eating after bariatric surgery. About 160 adults who had gastric bypass or sleeve gastrectomy a…

This early study tests a brain implant that monitors and stimulates brain activity to reduce loss-of-control eating in people with severe obesity who haven't been helped by other treatments. Only 6 participants will receive the device, and the main goal is to check safety and see…

This study tests whether the medication naltrexone/bupropion (Contrave) can help people who had bariatric surgery maintain control over eating and avoid weight regain. About 100 adults who previously responded to treatment for loss-of-control eating will receive either the medica…

This Phase 3 study tests the long-term safety and effectiveness of the drug solriamfetol in 300 adults with binge eating disorder. Participants take a daily pill (75, 150, or 300 mg) and are monitored for side effects and changes in binge eating. The study is open-label, meaning …

This study is testing a mobile app designed to help teenagers who struggle with binge eating and are overweight or at risk for obesity. The app uses strategies from cognitive-behavioral therapy to improve self-regulation and eating habits. Fifty teens will use the app for 16 week…

This study tests a therapy called RETELL that helps people with severe mental illness explore and reshape their life stories. The goal is to improve personal recovery, quality of life, and identity. Twenty adults with conditions like schizophrenia, bipolar disorder, or PTSD will …

This study tests whether watching short video lessons instead of reading chapters can help adults with binge eating disorder stop binge eating. Eighty adults will either watch weekly videos or read text-based materials for 13 weeks, with brief online coaching sessions. The goal i…

This pilot study is testing a type of talk therapy called Metacognitive Interpersonal Therapy (MIT-ED) for adults with various eating disorders, including those who are underweight. The therapy aims to help people understand and manage the negative thoughts and feelings that driv…

This pilot study tests a 10-week mindful eating self-help program for pregnant women who binge eat. Participants use a book and a smartphone app to learn mindful eating skills. The study aims to see if the program is feasible, acceptable, and helpful for reducing binge eating and…

This pilot study tests a specific type of drama therapy for people who have both a mental health condition (like depression or bipolar disorder) and a substance use disorder. Ten participants will attend weekly group drama therapy sessions for 12 weeks, then put on a performance.…

This small study tests whether a therapy called rTMS (repetitive transcranial magnetic stimulation) can reduce food cravings in adults who binge eat. Eight participants will receive six treatments, and brain scans will check for changes in reward pathways. The goal is to understa…

This study looks at whether peer mentors can support youth aged 16-24 with eating disorders as they move from youth to adult treatment. Participants are paired with a mentor for 3-6 months. The goal is to see if this approach is practical and helps keep patients motivated.

This study tests a new program that combines mindful eating with motivational interviewing to help people with overweight reduce binge eating. One hundred participants will either receive the full program (counseling plus daily meditation) or just daily meditation. The main goal …

This study tests whether the medication lisdexamfetamine (Vyvanse) can help people who experience loss-of-control eating after bariatric surgery and didn't improve with earlier treatments. About 60 adults who had gastric bypass or sleeve gastrectomy will receive either the drug o…

This study tests whether a two-week online self-compassionate letter-writing exercise can reduce shame and guilt about weight and body image, and increase readiness for treatment in people with eating disorders. 160 adults with anorexia, bulimia, or binge-eating disorder who are …

This study tests a group therapy called Awareness, Courage, and Love (ACL) for older adults with psychiatric disorders who feel lonely. The therapy focuses on mindfulness, sharing feelings, and building connections. Researchers want to see if the program is practical and helpful …

This early study tests whether a low-intensity focused ultrasound device can safely calm brain areas linked to food cravings in people with binge eating disorder. Fifteen adults with moderate to severe binge eating will receive a single session. The main goal is safety, but resea…

This study tests a type of therapy called cognitive remediation therapy (CRT) for women with eating disorders like anorexia, bulimia, or binge-eating disorder. CRT aims to improve thinking skills such as flexibility, planning, and impulse control, which are often affected in thes…

This pilot study tests a new self-guided program called RISE, designed to help people with eating disorders better sense and understand their body's internal signals, like hunger and fullness. The program includes four online modules with relaxation exercises, emotion management,…

This study tests whether a digital self-help app called Juniver can reduce symptoms of eating disorders like anorexia, bulimia, and binge eating. 300 adults in the UK and US will use the app for 12 weeks and report their symptoms. The app includes therapy-based lessons, interacti…

This study tests a 10-week program called 'Grow to Recovery' for people with mental illness. The program is co-led by a peer (someone who also has a mental illness) and a professional. Researchers want to see if it helps participants feel more hopeful and capable. 138 people are …

This study follows 180 children with overweight or obesity to see how their thinking skills (like memory and self-control) relate to eating habits and weight changes over time. Researchers will use brain tasks and interviews to understand these links. The goal is to find better w…

This study looks at how changing sleep patterns affects eating behavior and self-control in 120 children who are overweight or at risk for obesity. Researchers will monitor sleep, brain activity, and real-world eating to understand the link between sleep and weight gain. The goal…

This study looks at whether estrogen patches can improve mental flexibility and reward processing in young women (ages 14-35) with eating disorders linked to low estrogen. About 120 participants will receive either estrogen patches or placebo for 12 weeks. The goal is to understa…

This study follows 250 patients who have recovered from an eating disorder. Nurses will call them once a year for three years to check on their health and see if they relapse. The goal is to learn what factors might increase the risk of relapse, such as age or exercise habits.

This study looks at tobacco, cannabis, and other drug use among homeless and at-risk youth in downtown Ottawa. Researchers will follow 520 participants aged 16 and older who are homeless or insecurely housed and have a history of cannabis use and mental illness. The goal is to un…

This study follows 192 teens aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over 9 months. The goal is to…

This study uses brain scans to see how negative feelings change food choices and reward processing in people with binge eating disorders. Researchers will compare healthy individuals, those with obesity, and people with binge eating disorder or bulimia. The goal is to understand …