Achalasia

This pilot trial will test a disposable endoscope in 40 adults undergoing POEM procedures for achalasia or gastroparesis. The goal is to see if the single-use scope works as well as standard reusable scopes, potentially reducing infection risk. All participants receive standard c…

This study compares two versions of a minimally invasive procedure called POEM for treating achalasia, a swallowing disorder. The standard POEM often causes severe heartburn afterward. The new version, Sling-Fiber Preserving POEM, aims to reduce that risk by leaving certain stoma…

This study will compare two procedures—balloon dilation and per oral endoscopic myotomy (POEM)—in 70 children aged 3–17 with achalasia cardia, a condition where the esophagus can't push food into the stomach. Children will be randomly assigned to one procedure, and if it fails, t…

This pilot study compares recorded gut-directed hypnosis to an educational recording for hospitalized patients with chronic gut problems, such as irritable bowel syndrome or inflammatory bowel disease. Participants listen to the recordings over the phone while in the hospital for…

This trial tests whether making a horizontal (transverse) or vertical (longitudinal) cut in the esophagus lining during POEM surgery is faster and safer for people with achalasia, a swallowing disorder. About 140 adults in Colombia will be randomly assigned to one of the two inci…

This study compares two ways of doing a surgery called POEM for people with type II achalasia, a condition where the esophagus has trouble moving food into the stomach. The standard method uses a long tunnel under the lining of the esophagus, but this can cause bad acid reflux af…

This study looks at a procedure called POEM for people with achalasia, a condition where the esophagus has trouble moving food to the stomach. It compares patients getting POEM as their first treatment versus those who had a previous balloon dilation that didn't work well. Resear…

This study follows 30 people with achalasia (a swallowing disorder) for one year after their treatment. Researchers want to see if the weight gain that often happens after treatment leads to worse metabolic health, like fatty liver or higher blood sugar. Participants will have bl…

This study will look at 150 infants and children aged 1 month to 4 years who are admitted to a hospital gastroenterology unit with a gastrointestinal disease. The goal is to find out how common electrolyte disturbances (like low sodium or potassium) are in these children. By meas…