Cutting across or along? trial tests best way to start POEM for swallowing disorder
NCT ID NCT07425977
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether making a horizontal (transverse) or vertical (longitudinal) cut in the esophagus lining during POEM surgery is faster and safer for people with achalasia, a swallowing disorder. About 140 adults in Colombia will be randomly assigned to one of the two incision types. The main goal is to see how quickly the surgeon can enter the tunnel under the lining, and they will also track complications like bleeding or gas issues for up to 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
procedure: peroral endoscopic myotomy (POEM) with either transverse or longitudinal mucosal incision
What this could lead to
If successful, this could show that a transverse incision makes the POEM procedure faster and safer for treating achalasia.
What could go wrong
This is a small, early-phase trial with only 140 participants. The results may not apply to all patients, and the procedure carries standard risks like bleeding or infection.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alzate
Bogotá, Colombia
Contact Phone: •••-•••-•••• Email: •••••@•••••