Cutting across or along? trial tests best way to start POEM for swallowing disorder
NCT ID NCT07425977
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether making a horizontal (transverse) or vertical (longitudinal) cut in the esophagus lining during POEM surgery is faster and safer for people with achalasia, a swallowing disorder. About 140 adults in Colombia will be randomly assigned to one of the two incision types. The main goal is to see how quickly the surgeon can enter the tunnel under the lining, and they will also track complications like bleeding or gas issues for up to 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- procedure: peroral endoscopic myotomy (POEM) with either transverse or longitudinal mucosal incision
- What this could lead to
- If successful, this could show that a transverse incision makes the POEM procedure faster and safer for treating achalasia.
- What could go wrong
- This is a small, early-phase trial with only 140 participants. The results may not apply to all patients, and the procedure carries standard risks like bleeding or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Alzate
Bogotá, Colombia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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