Botox injection could replace surgery for Post-Esophagectomy stomach issues
NCT ID NCT06721520
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a Botox injection into the stomach valve works as well as a surgical cut to prevent food from emptying too slowly after esophagus removal. About 170 adults having elective esophagectomy will be randomly assigned to one of the two procedures. Researchers will track digestive symptoms and stomach emptying over two years to see if Botox is a good alternative.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum toxin A (Botox)
- What this could lead to
- If Botox works as well as surgery, it could offer a simpler, less invasive way to prevent stomach emptying problems after esophagus removal.
- What could go wrong
- This is a mid-stage trial with only 170 participants, so results may not apply to everyone. Botox effects are temporary, and the procedure still requires surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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