Can 3D motion capture reveal hidden breathing problems after esophageal cancer surgery?

NCT ID NCT03835273

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study investigates how chest wall movement and lung function change in people who had open surgery for esophageal cancer more than a year ago, compared to healthy volunteers. Researchers use a 3D motion capture system and wearable sensors to track chest movement during breathing and spirometry exercises. The goal is to objectively measure long-term respiratory changes that may contribute to high rates of lung complications after this surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help design better recovery programs to reduce lung complications after esophageal cancer surgery.
What could go wrong
This is an observational study with a small number of participants, so findings may not apply to all patients. It measures movement and function, not outcomes like infection rates.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

73 people

The number who actually took part.

Started

May 2019

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Three cohorts will be studied, equal in size. A total of 100 patients will be included in this study. One hundred patients who have undergone oesophagectomy for oesophageal cancer more than a year ago, 60 patients who have undergone open surgery and 40 healthy volunteers will be included as a control group with no underlying respiratory disease and no previous history of upper gastrointestinal surgery. Patients who have undergone oesophagectomy will be identified from existing databases by the direct care team of the patient. Healthy volunteers will be recruited from Imperial College through paper adverts.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Exposure group: 1. Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach. 2. Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study. * Control group: 1. Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery. 2. Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study. Exclusion Criteria: * Any participant who lacks capacity or is unable to provide informed consent. * Any participant younger than 18 or older than 90 years of age. * Any patient with evidence of cancer recurrence or on-going postoperative complication at more than one year following surgery for oesophageal cancer. * Any pregnant participant. * unable to or excluded from performing spirometry or respiratory muscle strength testing (non-invasive testing)

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Charing Cross Hospital

    London, W6 8RF, United Kingdom

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