Can 3D motion capture reveal hidden breathing problems after esophageal cancer surgery?
NCT ID NCT03835273
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study investigates how chest wall movement and lung function change in people who had open surgery for esophageal cancer more than a year ago, compared to healthy volunteers. Researchers use a 3D motion capture system and wearable sensors to track chest movement during breathing and spirometry exercises. The goal is to objectively measure long-term respiratory changes that may contribute to high rates of lung complications after this surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help design better recovery programs to reduce lung complications after esophageal cancer surgery.
- What could go wrong
- This is an observational study with a small number of participants, so findings may not apply to all patients. It measures movement and function, not outcomes like infection rates.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
73 people
The number who actually took part.
- Started
-
May 2019
- Finished
-
Aug 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Three cohorts will be studied, equal in size. A total of 100 patients will be included in this study. One hundred patients who have undergone oesophagectomy for oesophageal cancer more than a year ago, 60 patients who have undergone open surgery and 40 healthy volunteers will be included as a control group with no underlying respiratory disease and no previous history of upper gastrointestinal surgery. Patients who have undergone oesophagectomy will be identified from existing databases by the direct care team of the patient. Healthy volunteers will be recruited from Imperial College through paper adverts.
- Ages
-
18 to 90 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Exposure group: 1. Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach. 2. Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study. * Control group: 1. Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery. 2. Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study. Exclusion Criteria: * Any participant who lacks capacity or is unable to provide informed consent. * Any participant younger than 18 or older than 90 years of age. * Any patient with evidence of cancer recurrence or on-going postoperative complication at more than one year following surgery for oesophageal cancer. * Any pregnant participant. * unable to or excluded from performing spirometry or respiratory muscle strength testing (non-invasive testing)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Esophageal cancer are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Charing Cross Hospital
London, W6 8RF, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug shrink tumors that resist standard care?
- Could the anesthesia used during surgery influence whether esophageal cancer returns?
- Can an oral drug R01 fight advanced lung, stomach, and esophageal cancers?
- A single blood draw to detect five cancers before symptoms appear?
- Can custom vitamin pills fix nutrient gaps after stomach or esophageal cancer surgery?
- Can repeated MRI scans reveal how tumors respond to radiation?