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116076 trials found · Page 5586 of 5804
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Emergency surgery in pregnancy: new study aims to understand fetal outcomes
Knowledge-focused CompletedApproximately 1 in 500 pregnant women require non-obstetric surgery. Surgical care for the pregnant woman raises concern for complications adversely affecting pregnancy outcomes. The most common reason for surgery is acute appendicitis followed by gallbladder disease. Despite the…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Tiny study probes Tofacitinib's hidden effects on body composition
Knowledge-focused CompletedInflammatory rheumatic diseases (IRD), such as rheumatoid arthritis, are characterized by adverse changes in body composition. Lean mass and bone mineral density are usually reduced while adiposity (total fat mass, visceral adiposity…) is increased in comparison with healthy cont…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Stent registry shows Real-World results for blocked ureters
Knowledge-focused CompletedA multi-center global registry to obtain post-market safety and efficacy data on Boston Scientific Ureteral and Urinary Diversion Stents
Sponsor: Boston Scientific Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Scientists seek perfect antibiotic dose for young burn victims
Knowledge-focused CompletedConcentrations and effects of Ceftazidime in critically ill burn children are unpredictable and the risk of under-exposure may be associated with poor clinical outcomes. In addition, between-subject variability (BSV) is known to be substantial in critically ill burn children. Op…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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10 men revisited years after hypospadias Repair—What happened?
Knowledge-focused CompletedHypospadias is a frequent malformation. The definition of hypospadias is a ventral tissues hypoplasia, with an abnormal position of the urethral meatus, a chordee of the penis and an open foreskin. It can be associate with other genital malformation; in that case it can be classi…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Could HIV drugs help clear psoriasis? tiny study explores the idea
Disease control CompletedThe investigators hypothesize that the inhibition of endogenous reverse transcriptase would: (1) reduce excess cytosolic DNA, stress initiating the inflammatory loop at the origin of psoriatic lesions, and (2) interrupt the loop and lighten lesions
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Scientists snip skin during surgery to decode pain
Knowledge-focused CompletedBackground: Opioids are a class of drug that are often used to manage pain after a person has surgery. Because of the current opioid crisis, researchers want to improve ways to manage pain after surgery with fewer side effects. To do this, they need to understand pain better. In…
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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ICU nurses reunite with former patients in surprising Well-Being study
Knowledge-focused ENROLLING_BY_INVITATIONThe objective of this study is to learn more about the impact of a longitudinal encounter between critical care nurses and former intensive care unit patients. This study will enroll 10 patients that had been admitted in an ICU to meet with a former nurse that had taken care of t…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Baby bouncers and carriers put to the test for infant development
Knowledge-focused OngoingThe goal of this study is to experimentally test whether baby items can promote healthy infant development.
Phase: NA • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Neuro-Patch under the microscope: Real-World surgery study launched
Knowledge-focused OngoingThe aim of this study is to collect systematically and proactively data regarding the performance of Neuro-Patch, like complications and handling, under daily clinical practice when used as intended by the manufacturer
Sponsor: Aesculap AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Gut bugs may decide if your statin works
Knowledge-focused CompletedThere is evidence that the bacteria that naturally reside in the gut can influence how well we respond to medications. Therefore this study will look at how rosuvastatin, a medication used to lower cholesterol levels, may change the bacteria in the gut. Investigators will also ex…
Phase: PHASE4 • Sponsor: Sony Tuteja • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Tamiflu treatment may shorten flu isolation time, study suggests
Knowledge-focused OngoingSeasonal influenza is a frequent disorder with high impact on morbidity and mortality and significant burden on healthcare-related cost. In France, the 2018-2019 flu epidemic has led to 13,100 all-cause death including 9,900 death directly related to the viral infection. As cros…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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What happens to malnourished patients after hospital discharge? new study aims to find out
Knowledge-focused CompletedMalnourished patients are at risk of many complications, including infections, pressure ulcers and readmissions. Little is known about their care pathway after hospital discharge. This study aims to determine care pathways of malnourished patients after hospital discharge and to…
Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Scientists track Lactate's journey inside red blood cells during workouts
Knowledge-focused Recruiting nowThe goals of this clinical trial are: 1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of the SLC16A1 gene (rs1049434), and the amount of MCT…
Phase: NA • Sponsor: Technical University of Madrid • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:26 UTC
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Oxygen debate: lower levels may be safer for COPD patients
Disease control TerminatedChronic obstructive pulmonary disease (COPD) is a common disorder that affects approximately 400,000 Danish citizens. About 3,000-3,500 Danes die yearly because of the disorder, and the costs associated with hospital admissions are estimated to be 535 million Danish kroner (DKK).…
Phase: PHASE4 • Sponsor: Esbjerg Hospital - University Hospital of Southern Denmark • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New drug cenerimod put to the test: will it affect your heart or birth control?
Knowledge-focused CompletedThis is a single-center, randomized, double-blind for cenerimod, open-label for moxifloxacin, placebo- and moxifloxacin-controlled, parallel-group study to investigate the effect of cenerimod on the duration of the QT interval in healthy male and female participants. Participant…
Phase: PHASE1 • Sponsor: Viatris Innovation GmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Mexican heart failure patients studied for better care insights
Knowledge-focused CompletedCollect data on Mexican patients diagnosed with Heart Failure with reduced ejection fraction, their treatments, and their progress in a real-world environment. Additional objectives will be analyzed, such as mortality, the use of resources associated with the follow-up of this gr…
Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Tape trick: could a sticky strip beat Post-Workout pain?
Symptom relief Recruiting nowThe purpose of this study is to determine the effect of Kinesio tape on delayed onset muscle soreness of the biceps muscle of your arm following strenuous exercise of the bicep muscle.
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Ear device may tame arthritis pain without drugs
Symptom relief CompletedThe goal of this clinical trial is to learn if chronic self-administrated non-invasive vagus nerve stimulation works to improves the disease activity in a single asplenic patient suffering from rheumatoid arthritis. It will also learn about the safety of at-home chronic non-invas…
Phase: NA • Sponsor: Osteoflow Health Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Brain blood flow secrets revealed by breathing test
Knowledge-focused ENROLLING_BY_INVITATIONThe purpose of this research study is to better understand how blood flow and metabolism are different between normal controls and patients with disease. The investigators will examine brain blood flow and metabolism using magnetic resonance imaging (MRI). The brain's blood vess…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC