Scientists Fine-Tune diagnostic tools for autonomic nervous system disorders
NCT ID NCT03648905
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to improve how doctors test for autonomic failure, a condition where the body's automatic functions like blood pressure control don't work properly. Researchers will use advanced imaging, sweat tests, and skin biopsies in up to 89 adults with Parkinson's disease, multiple system atrophy, or related conditions. The goal is to make diagnoses more accurate and reliable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radioactive imaging agents (13N-Ammonia, 18F-DOPA, 11C-Methylreboxetine, 18F-Dopamine)
What this could lead to
If successful, this could lead to better diagnostic tests for autonomic failure, helping doctors identify and manage conditions like Parkinson's disease more accurately.
What could go wrong
This is an observational study focused on improving tests, not testing a new treatment. It is small (89 participants) and may not lead to immediate changes in patient care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States