Could a common antidepressant and ADHD drug curb alcohol cravings?
NCT ID NCT03575403
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether combining two existing drugs—duloxetine (an antidepressant) and methylphenidate (an ADHD medication)—could reduce the desire to drink alcohol in people with alcohol use disorder. Nineteen adults who were not seeking treatment participated in a lab setting. Researchers measured how much alcohol participants said they would buy at different prices, both before and after drinking, while on the drug combination or a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ALCOHOL USE DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Kentucky
Lexington, Kentucky, 40511, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a brain zapping headset curb relapse in addiction?
- Can a smartphone app tame Alcohol-Related liver disease?
- Calm in a room: can sensory therapy soothe the mind?
- Can a brief alcohol intervention improve mental health treatment?
- Smartphone support for sobriety: a trial tests digital tools in black communities
- Emergency room could be the starting point for alcohol addiction treatment