Could a common antidepressant and ADHD drug curb alcohol cravings?
NCT ID NCT03575403
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether combining two existing drugs—duloxetine (an antidepressant) and methylphenidate (an ADHD medication)—could reduce the desire to drink alcohol in people with alcohol use disorder. Nineteen adults who were not seeking treatment participated in a lab setting. Researchers measured how much alcohol participants said they would buy at different prices, both before and after drinking, while on the drug combination or a placebo.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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University of Kentucky
Lexington, Kentucky, 40511, United States