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116076 trials found · Page 5535 of 5804
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Cervical cancer study seeks clues in the blood
Knowledge-focused CompletedThis is a phase 0 clinical trial of molecular biomarkers in women with uterine cervix cancer. Women receive standard-of-care radiochemotherapy followed by brachytherapy. Blood samples are obtained to detect circulating levels of deoxyribonucleotides, human papillomavirus DNA, and…
Sponsor: Denise Fabian • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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AI takes on dental X-Rays: faster, but is it better?
Diagnosis CompletedThis study compares the accuracy and reliability of artificial intelligence (AI) software for analyzing dental X-rays to the traditional manual tracing method used by dentists. Lateral cephalometric radiographs are special X-rays of the head used in orthodontics (teeth straighte…
Sponsor: International Islamic University Malaysia • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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Vitamin B12a safety check: first step toward new gut disease treatments?
Knowledge-focused CompletedWe are planning a series of studies in individuals with ulcerative colitis, primary sclerosing cholangitis and pouchitis to determine if hydroxocobalamin is an effective therapy to treat these conditions. For these indications we are submitting INDs to the FDA as well as protocol…
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New drug for fatty liver disease takes first step in human testing
Knowledge-focused Completed\- Objectives: Primary objective\_To evaluate the safety and tolerability after single oral administration of the investigational product (IP), J2H-1702 in healthy female subjects. Secondary objective\_To evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) characteristic…
Phase: PHASE1 • Sponsor: J2H Biotech • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New dental implant design shows promise in small study
Knowledge-focused CompletedTo report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Teeing off after surgery: new study tracks Golfers' return to the fairway
Knowledge-focused OngoingAims The primary aim of this prospective, multi-centre study is to describe the rates of returning to golf following hip, knee and shoulder arthroplasty in an active golfing population. Secondary aims will include determining the timing of return to golf, changes in ability, hand…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Diabetes may impact dental pulp treatment success
Knowledge-focused CompletedThe aim of the present study will be directed to evaluate the clinical and radiographic success of adult pulpotomies in type 2 diabetic and non-diabetic patients.
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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What drives eyelid cancer in eastern morocco? a new study digs into the data
Knowledge-focused CompletedTwenty patients were included, comprising 11 women (55%) and 9 men (45%), with a mean age of 63.1 years. Chronic sun exposure was identified in 18 patients (90%). The lower eyelid was the most commonly affected site in 9 cases (45%). Basal cell carcinoma accounted for 15 tumors (…
Sponsor: Mohammed VI University Hospital • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Nose shape linked to allergies in kids?
Knowledge-focused CompletedAllergic rhinitis is one of the most common inflammatory conditions of the upper airway mucosa, especially in the pediatric population with a prevalence of approximately 25%. It is among the most common chronic inflammatory diseases globally and is caused by IgE-mediated reaction…
Sponsor: Federico II University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Which pill best eases root canal pain? new study puts three to the test
Symptom relief Completedafter 2 visit endodontics treatment, the analgesic efficacy of three different medications will be evaluated.
Phase: EARLY_PHASE1 • Sponsor: Armed Forces Institute of Dentistry, Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Brain tumor MRI study aims to uncover immune secrets
Knowledge-focused OngoingThe objective of this observational study is to investigate the characteristics of the tumor microenvironment in patients with brain tumors using multi-modal magnetic resonance imaging (MRI). The primary research question it aims to address is: • Can multi-modal MRI effectively …
Sponsor: Second Xiangya Hospital of Central South University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New video laryngoscope may help novice doctors intubate faster
Knowledge-focused CompletedThis study evaluated two different devices used for placing a breathing tube (endotracheal intubation) in adult patients undergoing elective surgery. The aim was to compare the King Vision videolaryngoscope, which has a camera and a guiding channel for the tube, with the traditio…
Phase: NA • Sponsor: Hitit University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:15 UTC
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Doctors as tax helpers: a new way to boost family health?
Knowledge-focused CompletedThe purpose of this study is to pilot test the feasibility and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of tax credits among low-income parents. The study will…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Heart failure and frailty: a closer look at hospitalized seniors
Knowledge-focused CompletedThe goal of this observational study is to investigate the prevalence and associated factors of frailty in hospitalized elderly patients with heart failure. The main questions it aims to answer are:(1) To clarify differences in demographic characteristics and test results (includ…
Sponsor: Zhejiang Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can a video-based course make nurses better at discussing end-of-life care?
Knowledge-focused CompletedThe aims of this study are to examine the effectiveness of a multi-media experiential training programme in advance care planning (ACP) for nursing staff in acute care settings. The main questions it aims to answer are: * can the programme enhance nurses' decision-support skills…
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New approach to tackle alcohol issues in Doctor's offices
Knowledge-focused OngoingThe Identification and Treatment of Alcohol Problems in Primary Care (iTAPP) Study is a pragmatic cluster randomized controlled intervention trial evaluating the effectiveness of the 15-Method as an identification and treatment tool for alcohol-related problems in Danish general …
Phase: NA • Sponsor: University of Southern Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Melatonin's hidden power: could it alter your Heart's response to cold?
Knowledge-focused Ongoingthe purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.
Phase: PHASE4 • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Food safety training put to the test: do workers learn better habits?
Knowledge-focused CompletedThis study was designed as a randomized controlled trial using a Solomon four-group experimental design to evaluate the effectiveness of a food safety training program. The study was conducted among food service employees working in municipal facilities. The Solomon four-group de…
Phase: NA • Sponsor: Kayseri University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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ECMO Patients' hidden infection risk under the microscope
Knowledge-focused OngoingNosocomial Infections (NI) are a common and dreadful complication for patients suffering from Acute Respiratory Distress Syndrome (ARDS) treated with Extracorporeal Membrane Oxygenation (ECMO). Unfortunately, no study has thoroughly evaluated NI in this fragile patient cohort. Ne…
Sponsor: Policlinico Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Saudi obesity study reveals heart disease links
Knowledge-focused CompletedThe purpose of this research study is to collect information on participants body weight, blood sugar levels, heart related diseases and lifestyle. The collected information will help estimate the prevalence of participants disease. This study will take about 6 months. However, …
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC