Could a natural hormone help people with obesity burn more calories?
NCT ID NCT03777215
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study tests whether a hormone called angiotensin-(1-7) can increase how many calories people with obesity burn while resting. Thirty adults with a BMI between 30 and 40 will receive the hormone or a placebo (saline) through an IV. Researchers will measure changes in energy use and look for signs of heat production in fat tissue.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Angiotensin-(1-7)
What this could lead to
If it works, this could point toward a new way to help people with obesity burn more calories at rest.
What could go wrong
This is a very early, small study with only 30 participants, so results may not apply broadly. It is designed to test a theory, not to prove a treatment works.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States