Could a natural hormone help people with obesity burn more calories?
NCT ID NCT03777215
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study tests whether a hormone called angiotensin-(1-7) can increase how many calories people with obesity burn while resting. Thirty adults with a BMI between 30 and 40 will receive the hormone or a placebo (saline) through an IV. Researchers will measure changes in energy use and look for signs of heat production in fat tissue.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Angiotensin-(1-7)
- What this could lead to
- If it works, this could point toward a new way to help people with obesity burn more calories at rest.
- What could go wrong
- This is a very early, small study with only 30 participants, so results may not apply broadly. It is designed to test a theory, not to prove a treatment works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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