Massive study aims to rewrite the rules for malignant hypertension

NCT ID NCT03755726

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is building a large database of 1,200 people with malignant hypertension, a severe form of high blood pressure that can damage organs quickly. Researchers will track patients for five years to learn how the disease behaves today and how doctors treat it. The goal is to update the definition and diagnosis of the condition, and eventually set the stage for better clinical trials and treatment recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could lead to better diagnostic criteria and more effective treatment guidelines for malignant hypertension.

What could go wrong

This is an observational registry, not a treatment trial. It will not directly test any new therapy, and results may take years to influence patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHP Bichat

    RECRUITING

    Paris, 75877, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Avicenne APHP

    RECRUITING

    Bobigny, 93009, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Martigues

    RECRUITING

    Martigues, 13500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Métropole

    RECRUITING

    Chambéry, 73011, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH d'Annecy

    RECRUITING

    Annecy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Chalon sur Saone

    RECRUITING

    Chalon-sur-Saône, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Dinard

    RECRUITING

    Dinard, 35800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Libourne

    RECRUITING

    Libourne, 33505, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de PAU

    RECRUITING

    Pau, 64000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de St Nazaire

    RECRUITING

    Saint-Nazaire, 44606, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Valenciennes

    RECRUITING

    Valenciennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de la côte Basque

    RECRUITING

    Bayonne, 64109, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU de Lille

    RECRUITING

    Lille, 59037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU - Hôpital Laennec

    RECRUITING

    Nantes, 44800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU - Hôpital St André

    RECRUITING

    Bordeaux, 33000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Michallon

    RECRUITING

    Grenoble, 38043, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Clermont FERRAND

    RECRUITING

    Clermont-Ferrand, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Montellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Pointe à Pitre

    NOT_YET_RECRUITING

    Pitres, 97159, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Poitiers

    RECRUITING

    Poitiers, 86021, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de ROUEN

    RECRUITING

    Rouen, 76000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Rennes

    RECRUITING

    Rennes, 35033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de St Etienne

    RECRUITING

    Saint-Etienne, 42055, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Strasbourg

    RECRUITING

    Strasbourg, 67000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Toulouse Rangueil

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Tours

    RECRUITING

    Tours, 37044, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinique Vert Coteau

    RECRUITING

    Marseille, 13012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinique sainte Clotilde

    RECRUITING

    Saint-Denis, 97400, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondation Adolphe de Rothschild

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital de la conception

    RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Européen Georges Pompidou

    RECRUITING

    Paris, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Henri Mondor

    RECRUITING

    Créteil, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Saint Joseph

    RECRUITING

    Paris, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Tenon

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Institute of Cardiology

    NOT_YET_RECRUITING

    Warsaw, Poland

    Contact Email: •••••@•••••

  • Pôle Santé Sud

    RECRUITING

    Le Mans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • hôpital de Haguenau

    RECRUITING

    Haguenau, 67504, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••