Massive study aims to rewrite the rules for malignant hypertension
NCT ID NCT03755726
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is building a large database of 1,200 people with malignant hypertension, a severe form of high blood pressure that can damage organs quickly. Researchers will track patients for five years to learn how the disease behaves today and how doctors treat it. The goal is to update the definition and diagnosis of the condition, and eventually set the stage for better clinical trials and treatment recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could lead to better diagnostic criteria and more effective treatment guidelines for malignant hypertension.
- What could go wrong
- This is an observational registry, not a treatment trial. It will not directly test any new therapy, and results may take years to influence patient care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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APHP Bichat
RECRUITINGParis, 75877, France
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Avicenne APHP
RECRUITINGBobigny, 93009, France
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CH Martigues
RECRUITINGMartigues, 13500, France
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CH Métropole
RECRUITINGChambéry, 73011, France
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CH d'Annecy
RECRUITINGAnnecy, France
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CH de Chalon sur Saone
RECRUITINGChalon-sur-Saône, France
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CH de Dinard
RECRUITINGDinard, 35800, France
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CH de Libourne
RECRUITINGLibourne, 33505, France
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CH de PAU
RECRUITINGPau, 64000, France
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CH de St Nazaire
RECRUITINGSaint-Nazaire, 44606, France
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CH de Valenciennes
RECRUITINGValenciennes, France
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CH de la côte Basque
RECRUITINGBayonne, 64109, France
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CHRU de Lille
RECRUITINGLille, 59037, France
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CHU - Hôpital Laennec
RECRUITINGNantes, 44800, France
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CHU - Hôpital St André
RECRUITINGBordeaux, 33000, France
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CHU Michallon
RECRUITINGGrenoble, 38043, France
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CHU de Clermont FERRAND
RECRUITINGClermont-Ferrand, France
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CHU de Montellier
RECRUITINGMontpellier, France
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CHU de Pointe à Pitre
NOT_YET_RECRUITINGPitres, 97159, France
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CHU de Poitiers
RECRUITINGPoitiers, 86021, France
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CHU de ROUEN
RECRUITINGRouen, 76000, France
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CHU de Rennes
RECRUITINGRennes, 35033, France
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CHU de St Etienne
RECRUITINGSaint-Etienne, 42055, France
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CHU de Strasbourg
RECRUITINGStrasbourg, 67000, France
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CHU de Toulouse Rangueil
RECRUITINGToulouse, 31059, France
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CHU de Tours
RECRUITINGTours, 37044, France
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Clinique Vert Coteau
RECRUITINGMarseille, 13012, France
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Clinique sainte Clotilde
RECRUITINGSaint-Denis, 97400, France
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Fondation Adolphe de Rothschild
RECRUITINGParis, France
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Hopital de la conception
RECRUITINGMarseille, 13385, France
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Hôpital Européen Georges Pompidou
RECRUITINGParis, 75015, France
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Hôpital Henri Mondor
RECRUITINGCréteil, France
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Hôpital Saint Joseph
RECRUITINGParis, 75014, France
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Hôpital Tenon
RECRUITINGParis, France
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National Institute of Cardiology
NOT_YET_RECRUITINGWarsaw, Poland
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Pôle Santé Sud
RECRUITINGLe Mans, France
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hôpital de Haguenau
RECRUITINGHaguenau, 67504, France