Could your own nerve cells help heal severe injuries?
NCT ID NCT03999424
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tested whether adding a patient's own Schwann cells (nerve-supporting cells) to a nerve graft could safely improve recovery after severe peripheral nerve injury. Five adults with large nerve gaps received the cell-enhanced graft. The main goal was safety, checking for side effects and signs of nerve regrowth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
autologous human Schwann cells
What this could lead to
If it works, this could point toward a treatment that improves nerve regrowth and function after severe injuries.
What could go wrong
This is a very early Phase 1 safety trial with only 5 people. It is too small to prove effectiveness, and the approach may not work or could cause side effects like pain or nerve changes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Miami
Miami, Florida, 33136, United States