CAR-T Therapy's hidden toll on the brain: new study investigates
NCT ID NCT04107285
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 120 adults with lymphoma who are receiving CAR-T cell therapy. Researchers will test memory, attention, and other thinking skills, and perform brain MRIs and blood tests before and after treatment. The goal is to understand how CAR-T therapy may affect the brain and cognition over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors predict and manage cognitive side effects of CAR-T therapy, improving patient quality of life.
What could go wrong
This is an observational study, not testing a new treatment. It may not lead to direct changes in care, and results may not apply to all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LYMPHOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-••••
Locations
-
Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-••••