CAR-T Therapy's hidden toll on the brain: new study investigates
NCT ID NCT04107285
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 120 adults with lymphoma who are receiving CAR-T cell therapy. Researchers will test memory, attention, and other thinking skills, and perform brain MRIs and blood tests before and after treatment. The goal is to understand how CAR-T therapy may affect the brain and cognition over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors predict and manage cognitive side effects of CAR-T therapy, improving patient quality of life.
- What could go wrong
- This is an observational study, not testing a new treatment. It may not lead to direct changes in care, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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