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116076 trials found · Page 5479 of 5804
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Creatine supplement side effects under the microscope
Knowledge-focused CompletedThis study aimed to investigate the incidence and severity of GI symptoms associated with daily CM supplementation, with and without a loading phase, in healthy male and female adults.
Sponsor: Vireo Systems, Inc. • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:19 UTC
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Air filter study in cameroon operating room shows promise
Knowledge-focused CompletedThis research project is evaluating an air filtration system that is supposed to be adapted to the context, highly efficient and affordable. This air filtration system for operating theatres has been in use at Mbouo-Bandjoun hospital in Cameroon since 2019, with no incidents reco…
Sponsor: Christian Doll • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New breathing device may help CF patients produce mucus for testing
Knowledge-focused CompletedThis is a small pilot study with the goal of identifying a superior sputum collection method in Cystic Fibrosis patients unable to produce a sputum. Participants will use the Volara System during clinic visit in an attempt to produce sputum.
Phase: NA • Sponsor: Daniel J. Weiner • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Brain scans aim to unlock secrets of autism and depression
Knowledge-focused ENROLLING_BY_INVITATIONThe goal of this observational study is to investigate the brain physiological responses in depression and autism. The main questions aim to answer are: 1. Comparing the ratios of cortical excitation and inhibition among four groups: autism group, autism with depression group, d…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Can a fun sports program get rural girls moving?
Knowledge-focused ENROLLING_BY_INVITATIONThe goal of this study is to examine the impact of a 12-week sports sampling and physical literacy program on rural girls' physical activity.
Phase: NA • Sponsor: San Diego State University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:19 UTC
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Meal timing may matter for new sickle cell drug
Knowledge-focused CompletedThe purpose of this study is to evaluate the effect of food on the amount of etavopivat in the bloodstream of healthy participants. Participants will take a single oral dose of etavopivat following a high-fat meal (i.e. fed) and on an empty stomach (i.e fasted) on two separate oc…
Phase: PHASE1 • Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Soliris safety checked in korean patients
Knowledge-focused CompletedAs part of a post-approval commitment, the Korean health authority requests a study to characterize safety and effectiveness in patients who are treated with Soliris in normal clinical practice settings. This study is designed to assess the known safety profile or identify previo…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New IBD drug candidate SPH7854 begins first human safety tests
Knowledge-focused Recruiting nowTo evaluate the safety of SPH7854 in healthy subjects.
Phase: EARLY_PHASE1 • Sponsor: Shanghai Pharmaceuticals Holding Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Microwaves may offer new way to check breast health
Knowledge-focused CompletedThe goal of this observational study is to use a low-powered microwave imaging system to provide insight into the correlation of electrical properties of breast tissue at microwave frequencies and breast density obtained from mammograms in healthy women between the ages of 18 and…
Phase: NA • Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Tooth rebuild before gum graft: does it help cover exposed roots?
Disease control TerminatedThe goal of this prospective cohort study is to evaluate the effect of non-carious cervical lesions (NCCLs) on the outcome of root coverage therapy. The main question it aims to answer is: In gingival recessions associated with NCCLs, characterized by an undetectable cemento-enam…
Phase: NA • Sponsor: Gonzalo Blasi • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Prison education program boosts breast cancer awareness
Knowledge-focused Completedthis study evaluated the impact of breast cancer education on knowledge and awareness among incarcerated women using a quasi-experimental design.
Phase: NA • Sponsor: Hitit University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Punch vs cut: which dental implant method wins?
Knowledge-focused Completedthis study aimed to evaluate both clinically and radiographically the effect of flapless versus flap techniques on initial crestal bone loss and osseointegration of dental implants in lower posterior area. the study is to designed to observe the clinical outcomes such as primary …
Phase: NA • Sponsor: Tanta University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:18 UTC
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Breathing settings during surgery may impact brain pressure, study finds
Knowledge-focused CompletedThis prospective interventional study will evaluate the effects of applying positive end-expiratory pressure (PEEP) at 10 cmH₂O on optic nerve sheath diameter (ONSD) in patients undergoing elective laparoscopic cholecystectomy under general anesthesia. A total of approximately 40…
Phase: NA • Sponsor: Nigde Omer Halisdemir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Acupuncture needles to kickstart labor? tiny study investigates
Knowledge-focused TerminatedCervical ripening is a medical treatment that can cause physical or emotional discomfort in pregnant women and is not without risks. This is a pilot study to assess feasibility and calculate the number of participants necessary for a complete clinical trial. The aim is to evaluat…
Phase: NA • Sponsor: Consorci Sanitari de l'Alt Penedès i Garraf • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Heart pump brain risk study halted after just 6 patients
Knowledge-focused TerminatedThere is a dire need to establish normative values for transcranial Doppler(TCD) derived cerebral blood flow parameters for each type of Mechanical circulatory support (MCS) device and explore the relationship between the MCS device's systemic flow dynamics and TCD based cerebral…
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Digital spirometer shows promise for boosting lung health
Knowledge-focused CompletedThis prospective single-group pre-post study evaluated whether digital incentive spirometry training using the TryBreath system could improve pulmonary function, respiratory muscle strength, exercise capacity, and symptom scores in healthy adults. Participants completed a 3-week …
Phase: NA • Sponsor: Taipei Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New trazodone formula tested for similarity to current version
Knowledge-focused CompletedTwo way, two parallel groups, crossover study to compare the bioavailability of 150 mg and 300 mg trazodone hydrochloride (new polymer) (Angelini Pharma S.p.A.) vs. 150 mg and 300 mg trazodone hydrochloride Contramid® (Angelini Pharma S.p.A.) at steady-state in 64 Healthy Volunte…
Phase: PHASE1 • Sponsor: Aziende Chimiche Riunite Angelini Francesco S.p.A • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:07 UTC
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Flu vaccine showdown: 2023 vs 2024 formula tested in small study
Knowledge-focused CompletedEvery 1-2 years, the seasonal influenza vaccine composition changes to include updated viruses, yet the precise effects of updating the vaccine remain understudied. Since the vaccine formulation for each season (with a season defined as starting in July and ending the following J…
Phase: PHASE4 • Sponsor: La Jolla Institute for Immunology • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New MRI technique could reveal hidden tendon damage
Knowledge-focused CompletedThe goal of this observational study is to understand how diffusion tensor imaging (DTI) relates to other traditional measures and knee function. The main question it aims to answer is: Will regions of known patellar tendon pathology present with smaller DTI scalar parameters, s…
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Australian study reveals how breast cancer drugs are actually used
Knowledge-focused CompletedThe purpose of this study is to learn about how a class of medicines called CDK4/6 inhibitors, are used for the treatment of breast cancer in patients in Australia. The study looks at how the CDK4/6 inhibitor class of drugs are used for treating breast cancer that is advanced or …
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC