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127005 trials found · Page 5347 of 6351
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Brain zapping study seeks clues to Autism's social challenges
Knowledge-focused Recruiting nowThe goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.
Sponsor: American University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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MRI and AI join forces to track spine disease activity
Knowledge-focused Recruiting nowThis study aims to further improve and expand the WB-MRI imaging evaluation cohort of axSpA patients to complete dynamic follow-up and condition assessment. Based on the WB-MRI features, the association of WB-MRI signs with disease activity, inflammation, and structural damage wi…
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Does anesthesia flow rate affect inflammation in obesity surgery?
Knowledge-focused CompletedThis retrospective observational study aimed to compare the effects of low-flow and standard-flow sevoflurane anesthesia on perioperative inflammatory responses in patients undergoing laparoscopic sleeve gastrectomy for obesity. Data were obtained from the anesthesia and laborato…
Sponsor: Adana City Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Warm showers during labor: a soothing strategy for pain relief?
Symptom relief CompletedThe use of non-pharmacological methods in labor pain is very important in order to improve the birth process, increase comfort and provide relaxation. The role of midwives, acting as patient advocate is to maintain comfort throughout the birth process. In order to do this, she sh…
Sponsor: Gulhane School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New asthma treatment for kids who Don't respond to standard steroids?
Disease control Stopped earlyMost children with asthma have concurrent atopy (allergic inflammation), which is associated with an improved response to ICS. However, the absence of an atopic phenotype is associated with a poorer ICS response, leaving clinicians with limited treatment options. The nonatopic as…
Phase 2 • Sponsor: Nemours Children's Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Toe walking study reveals best treatment and genetic links
Knowledge-focused CompletedTo compare and contrast the clinical, gait and parent-reported outcomes following either non-operative (casting) or operative treatment for children with idiopathic toe walking (ITW) and determine whether there are specific genes associated with ITW.
Sponsor: Shriners Hospitals for Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Brain training via telehealth shows promise for veterans battling depression and suicide risk
Symptom relief CompletedDespite large-scale, nationwide efforts to better address suicidal behavior in Veterans at high risk, the development of interventions that target some of the key risk factors associated with suicide remains limited. This study aims to collect pilot data to test feasibility/accep…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Real-Time margin check during rectal cancer surgery may cut recurrence
Knowledge-focused CompletedThis study aims to improve the safety of distal surgical margins in patients with middle and low rectal cancer who receive neoadjuvant radiotherapy. Although magnetic resonance imaging and colonoscopic evaluation after neoadjuvant radiotherapy may suggest complete or near-complet…
Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Parkinson's Patients' hospital stays under the microscope
Knowledge-focused CompletedThe goal of this observational study is to investigate the causes of hospitalisation via emergency services in patients with degenerative parkinsonian syndromes. All causes of hospital admission through the emergency department among patients with Parkinson's-related disorders w…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Blood test may reveal hidden inflammation in back pain patients
Knowledge-focused CompletedThis retrospective cross-sectional observational study aims to evaluate the association between the C-reactive protein-albumin-lymphocyte (CALLY) index and disease activity and functional status in patients with ankylosing spondylitis. Medical records of adult patients followed b…
Sponsor: Bursa City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Tongue position after jaw surgery may determine Long-Term success
Knowledge-focused CompletedThe anterior gap is defined by a lack of contact between the upper and lower dental arches. It is mainly due to the persistence of infantile swallowing during and after childhood, i.e. interposition of the tongue between the two dental arches. Patients presenting with an anteri…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Massive diabetes study launches to uncover Long-Term trends
Knowledge-focused Recruiting nowThe aim of the China Diabetes Type 1 Study (CD1S) is to conduct a nationwide type 1 diabetes (T1D) registry study in patients with T1D and in pediatric adolescent patients with diabetes who had an age of onset \<= 20 years. CD1S compromises a retrospective study enrolling inpati…
Sponsor: Second Xiangya Hospital of Central South University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Nerve block volume may cut opioid use after hysterectomy
Symptom relief Completedhis study aims to investigate the effects of different volumes of ultrasound-guided erector spinae plane block (ESPB) on postoperative pain and opioid consumption in patients undergoing total abdominal hysterectomy. The researchers aim to determine whether varying the volume of l…
Sponsor: Şule Arıcan • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New study tests better stitching to prevent leaks after weight-loss surgery
Symptom relief CompletedThis prospective comparative cohort study was conducted in accordance with the Declaration of Helsinki and approved by the Ethical Committee of the Medical Research Institute. All consecutive patients undergoing laparoscopic sleeve gastrectomy (LSG) between January 2022 and June …
Sponsor: Al-Kindy Teaching Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Digital twin predicts muscle gains: a new era for personalized fitness?
Knowledge-focused CompletedBackground: Muscular strength training interventions have long been a cornerstone in the prevention, non-surgical management and rehabilitation of the entire spectrum of musculoskeletal injuries and diseases. The key goal of strength training, especially during rehabilitation, is…
Sponsor: Silvio Lorenzetti • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Why does kidney stone pain come back? new study tracks 878 patients
Knowledge-focused CompletedRenal colic (RC) is a common pathology in emergency medicine, with a high risk of recurrence. Early recurrence remains a major concern, affecting up to 30% of patients, with around 84% of these recurrences occurring within two days of the initial episode , despite preventive meas…
Sponsor: University of Monastir • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Robot suit training may ease bowel problems in spinal cord injury
Symptom relief CompletedThe purpose of the study is to assess the effects of exoskeleton training on neurogenic bowel disorders in spinal cord injury/ disease.
Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Your iPhone could help monitor psoriasis: new study tests smartphone tracking
Knowledge-focused OngoingThe purpose of this study is to understand variation in the symptoms of psoriasis and psoriatic arthritis using simple, scalable smartphone-based measurements. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
Sponsor: Sage Bionetworks • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Dental implant infection showdown: which cleaning method wins?
Disease control OngoingTwo groups are aimed at being investigated in three centers (CICOM, Clinica Branemark and Clinica Joan Pi) * Test group: Group electrolytic approach (EA): Mechanical detoxification using curettes + NiTi brushes + EA (GalvoSurge) during 2 minutes * Control group: Group hydrogen p…
Sponsor: Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Could a simple questionnaire replace the gold standard for measuring salt intake?
Knowledge-focused CompletedDETERMINATION OF URINARY SODIUM EXCRETION AND DIETARY SODIUM INTAKE IN ADULTS BY DEVELOPING A FOOD FREQUENCY QUESTIONNAIRE FOR ADDED-SALT FOODS Dear Participant, A doctoral thesis study titled "Determination of Urinary Sodium Excretion and Dietary Sodium Intake in Adults by Devel…
Sponsor: Toros University • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC