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116076 trials found · Page 4828 of 5804
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Ultrasound reveals hidden brain risks during aortic stent surgery
Knowledge-focused OngoingThis is an observational cohort study addressing the incidence of cerebral microemboli and alterations of cerebral hemodynamic physiology of the Relay®Branch thoracic stent-graft system.
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Can your genes prevent bad drug reactions? new study aims to find out
Knowledge-focused Recruiting nowThe investigator's primary aim is to evaluate polypharmacy-associated adverse drug reactions (ADR) in a pilot study of at-risk patients using state-of-the-art pharmacogenomic technology and to use this information to make recommendations for optimization of pharmacotherapy regime…
Sponsor: Texas A&M University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:34 UTC
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Can a smartwatch replace doctor visits for cancer patients?
Knowledge-focused CompletedThis study investigates a device that closely monitors vital signs, as well as a smartphone application (app) that allows patients to respond to different questions and tests that will monitor for new symptoms. This study may help researchers understand if wearing the device is a…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Can teaching caregivers about swallowing issues after stroke make a difference?
Knowledge-focused CompletedThis randomized controlled experimental study was conducted to evaluate the effects of dysphagia management training provided to caregivers of stroke patients receiving home care. The sample size was determined using power analysis (n=84). Data were collected using the Personal I…
Phase: NA • Sponsor: Uludag University • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Radiation plus chemo for pancreatic cancer pain: trial ends early
Symptom relief TerminatedThe MASPAC trial investigates the added benefit of MR-guided adaptive SBRT of the primary tumor embedded between standard chemotherapy cycles for pain control and prevention of pain in patients with metastatic PDAC (mPDAC).
Phase: PHASE2 • Sponsor: Ludwig-Maximilians - University of Munich • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Terpenes: the next frontier in pain relief?
Symptom relief OngoingThe purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.
Phase: PHASE1 • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Could a simple implant spare men from urinary pain after prostate radiation?
Symptom relief TerminatedMany patients may face long-term urinary side effects following stereotactic body radiation therapy (SBRT), including increased urinary frequency, dysuria, and nocturia. The investigator hypothesizes that Urolift, which represents a novel minimally invasive therapy, may reduce ac…
Phase: NA • Sponsor: Northwell Health • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could a natural extract boost fertility treatment in PCOS?
Disease control Recruiting nowThe effect of combination therapy dlbs 3233 and clomifen citrate vs clomifen citrate on homa ir, maturation follicle, and menstrual cycle in PCOS cases at Muhammadiyah Asri Medical Center Hospital
Phase: EARLY_PHASE1 • Sponsor: Inlacinpenelitian • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Study tests whether a friendly face in the delivery room eases labor pain
Symptom relief CompletedProblem Statement: In the governmental hospitals it is not allow to presence one of family with woman during child birth in labor room that affects negatively in pregnant emotion and feel more anxious especially primigravida although it effect positively in labor process and out…
Phase: NA • Sponsor: The Hashemite University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New study follows 500 seniors with heart devices to improve care decisions
Knowledge-focused ENROLLING_BY_INVITATIONThis is a prospective cohort study of older patients receiving implantable cardioverter-defibrillators. The purpose of the TRACER-ICD study is to conduct a prospective cohort investigation with the goal of 500 patients age \>65 receiving new primary prevention implantable cardiov…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New eye implant for wet AMD under safety spotlight
Disease control Recruiting nowThis study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W).
Phase: PHASE4 • Sponsor: Genentech, Inc. • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Could a bone drug help fight ovarian cancer?
Disease control OngoingThis is a randomized pilot trial of weekly paclitaxel and bevacizumab with or without zoledronic acid in women with platinum-resistant epithelial ovarian cancer with 1-2 prior regimens for recurrence.
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Nerve blocks slash pain after keyhole heart surgery
Symptom relief CompletedThe overall research plan is PECS/SAP blocks with liposomal bupivacaine improve the Overall Benefit Analgesia Score averaged over the postoperative days 1, 2, and 3. A 20% reduction on geometric means (i.e., true ratio of geometric means of 0.80) in OBAS will be considered the mi…
Phase: PHASE4 • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Dental implants may 'Sink' as you age – study seeks answers
Knowledge-focused Recruiting nowLosing a tooth in the front part of the upper jaw can affect both appearance and the ability to bite and chew. Treatment to replace missing teeth is therefore often required. Such treatment may be burdensome for the individual and can involve substantial costs for both the patien…
Sponsor: Region Västerbotten • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Small study aims to perfect bleeding drug dose for joint replacements
Knowledge-focused CompletedOver 1.7 million hip and knee replacements are performed every year worldwide. These surgeries are associated with high blood loss and transfusion rates. In older patients, the high blood loss can result in postoperative anemia. Anemia is a condition where there is a lack of heal…
Phase: PHASE2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New pain block cuts opioid need after ACL surgery
Symptom relief CompletedThis randomised clinical trial evaluates the analgesia provided by an iPack block associated with an adductor canal block in patients who undergo anterior cruciate ligament reconstruction surgery, compared to an adductor canal block alone. The objective is to prove the superiorit…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Lung cancer clues: old data may reveal best Pre-Surgery treatments
Knowledge-focused Recruiting nowThis is a non-interventional, observational, multicenter and retrospective study. Being limited to the collection of patient data already filled in the Tumor Thoracic Registry data base and the data from stage IIIA clinical trials case report forms.
Sponsor: Fundación GECP • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Experimental lymphoma drug CPO107 tested in small early trial
Disease control TerminatedThis first-in-human Phase 1 study will be a multicenter, dose-escalating, single-agent study conducted in patients with advanced CD20-associated hematological cancers for which the investigator determines there to be no other higher priority therapies available.
Phase: PHASE1 • Sponsor: Conjupro Biotherapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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What matters more: cure or quality of life? new study asks rectal cancer patients
Knowledge-focused Recruiting nowThis study is aiming to look into patients' treatment preferences and their socio economic background as well as the exploration of thought processes leading to these preferences. It will integrate, in two exploratory questionnaires, the three most common treatment schema (standa…
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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UCLA tests if naltrexone cancels the Fear-Busting power of a hug
Knowledge-focused ENROLLING_BY_INVITATIONUniversity of California, Los Angeles researchers will recruit healthy participants (age 18-35) to participate in a study examining whether the administration of naltrexone, an opioid antagonist, eliminates the ability of social support figure reminders to enhance fear extinction…
Phase: EARLY_PHASE1 • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC