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116076 trials found · Page 4809 of 5804
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Gut bugs and night shifts: a recipe for diabetes risk?
Knowledge-focused OngoingThe primary aims of the current study: * using L-carnitine supplementation modulate the level of plasma trimethylamine N-oxide to assess its effect on circulating cytokines related to diabetes and metabolic syndrome; * using simulated night-shift work intervention as a stress fa…
Phase: NA • Sponsor: Poznan University of Physical Education • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Autism motor skills under the microscope: new study seeks answers
Knowledge-focused Recruiting nowThis research is a case-control study aiming to characterize motor peculiarities (objective quantitative and qualitative measures) and its psycho-physiological correlates of children with ASD.
Phase: NA • Sponsor: Centre Hospitalier Charles Perrens, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Can positive music help lift the negativity bias in depression?
Knowledge-focused CompletedDepressed subjects display a cognitive bias of information processing and emotional self-regulation, which reinforces negative experiences more than positive ones, known as the negativity bias. The link between depressive disorder and negativity bias has been much studied in term…
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Scientists create first detailed map of spinal cord tracts in healthy volunteers
Knowledge-focused CompletedToday, Spinal cord pathologies, whether are tumoral, vascular, traumatic, malformative, inflammatory, or degenerative still constitute a major medico-surgical challenge due to the particular anatomy of the spinal cord. Indeed, the spinal fibers (whether they have a sensory or mot…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:47 UTC
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Brainwave training shows promise for veteran memory decline
Knowledge-focused CompletedMilitary deployment is associated with increased risk of mild cognitive impairment (MCI). Combat stress related memory deficits has been well documented. Mild cognitive impairment such as memory deficits are the most common and earliest symptoms of Alzheimer's disease and related…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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New heart mapping technique could sharpen ablation accuracy
Knowledge-focused Recruiting nowThe aim of the present work is to analyze the capacity of high resolution mapping systems to determine the precise location of the AV node and peri-nodal slow-conducting pathways, using standard recording parameters, but also off-line additional filter changes and additional tech…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Jaw implants aim to boost life quality after surgery
Symptom relief CompletedThis study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK®) used for orthognathic surgery.
Sponsor: Global D • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Hormone therapy shows promise in preventing relapse in postpartum meth users
Prevention CompletedThe PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of 200 mg oral micronized progesterone twice daily or placebo. The aims of this study are to assess t…
Phase: EARLY_PHASE1 • Sponsor: University of Utah • Aim: Prevention
Last updated Jun 27, 2026 13:01 UTC
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New registry tracks ESD success for GI lesions in 1,000 patients
Knowledge-focused Recruiting nowThis registry is to evaluate the procedural and clinical outcomes in patients undergoing endoscopic submucosal dissection. All patients will receive standard of medical care and no experimental interventions will be performed.
Sponsor: AdventHealth • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can bias training help doctors talk fairly to all families?
Knowledge-focused CompletedThis study aims to determine the ways in which clinician implicit racial biases affect clinician communication with family members of patients near the end of life and to test a novel physician training intervention to reduce the effects of implicit racial bias on quality of comm…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Spine surgery data bank launched to improve future care
Knowledge-focused Recruiting nowEstablish a data repository of patients who have undergone single, two-, or three-level lumbar instrumented arthrodesis procedures supplemented by the Implanet Jazz System.
Sponsor: Francis Farhadi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Could your surroundings fuel thyroid cancer? new study investigates
Knowledge-focused Recruiting nowThyroid cancer incidence has been steadily increasing and has nearly tripled since the 1970's in the US and worldwide. Early detection of small, papillary thyroid cancers using high quality diagnostic imaging explains only about 50% of this increased incidence, suggesting that th…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Does anesthesia choice impact liver cancer recurrence?
Knowledge-focused CompletedEvaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic Processes The goal of this clinical trial is to evaluate of the involvement of Neutrophil extracellular traps in the evolution of hepatocellular cancer. The main questions it aims to a…
Phase: NA • Sponsor: Iuliu Hatieganu University of Medicine and Pharmacy • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Blood-derived face cream boosts skin moisture and elasticity in small trial
Symptom relief CompletedThe study evaluates the effectiveness of cosmetic preparations containing PRF, conducted through in vivo studies. Material and Methods: The study involved 20 healthy volunteers (aged 20-40) who received three identically packaged creams to be applied to specific facial areas. For…
Phase: PHASE2 • Sponsor: Poznan University of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Can peer support help public housing residents kick the habit?
Disease control CompletedThis project seeks to determine the effectiveness of two types of interventions to reduce exposure to secondhand smoke in residential buildings. One intervention is geared toward all building residents (resident endorsement) and the other targets smokers (smoking reduction via re…
Phase: NA • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Robot buddy for dementia: can a chatty machine boost mood?
Knowledge-focused CompletedThis implementation study will be conducted to test a Socially-Assistive Robot (SAR) system for residents in an Assisted Living environment. The goal of the SAR system is to enhance social engagement and connectedness. The system engages residents via robot-facilitated activities…
Phase: NA • Sponsor: SimpleC, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Opioid-Free anesthesia shows promise for hip surgery pain
Symptom relief CompletedTotal hip arthroplasty (THA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery. Postoperative pain management in THA requires multimodal analgesia, combining drugs and in…
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Japan study tracks Sogroya's Long-Term safety in severe hormone deficiency
Disease control OngoingParticipants are invited to take part in this study because they have AGHD (only severe case). The purpose of this study is to assess long term safety and effectiveness of Sogroya® in patients with AGHD (only severe case) under normal clinical practice condition in Japan. Partici…
Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New training aims to boost risk awareness in drunk drivers
Knowledge-focused CompletedThis study aims to test the efficacy of experiential-based training to increase DUI offenders' perceptions or risk associated with alcohol use.
Phase: NA • Sponsor: Mark Fillmore • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Can simple pelvic floor exercises ease bladder issues in MS?
Symptom relief CompletedThe aim of this study was to compare the effects of pelvic floor strengthening and relaxation exercises on lower urinary tract dysfunction (LUTD), depression and quality of life (QoL) in women with Multiple Sclerosis (WwMS). The main questions it aims to answer are: * Are pelvic…
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated Jun 27, 2026 11:04 UTC