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116076 trials found · Page 4553 of 5804
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New exercise combo shows promise for bladder control in MS
Symptom relief CompletedThe goal of this randomized controlled trial is to investigate whether adding Dynamic Neuromuscular Stabilization (DNS)-based training to Pelvic Floor Muscle Training (PFMT) can improve lower urinary tract symptoms (LUTS) and pelvic floor functions in women with multiple sclerosi…
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can training caregivers keep kids safer at home?
Prevention CompletedThe investigators will pilot test (N=100 caregivers of children ages 3-4 years) the effects of a caregiver supervision intervention on caregivers' supervision and children's injury frequency using a Randomized Controlled Trial (RCT) design. The control group will receive Services…
Phase: NA • Sponsor: Western Michigan University • Aim: Prevention
Last updated Jun 27, 2026 07:51 UTC
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Cheaper dental implant materials could boost gum health and looks
Disease control CompletedThe study focuses on the critical role of the gingival emergence profile in the success of dental implants, emphasizing its importance for both peri-implant health and esthetics. The research aims to evaluate and compare the effectiveness of two common, cost-effective dental mate…
Phase: NA • Sponsor: Amrita Institute of Medical Sciences & Research Center • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Future-Focused parenting: a new tool to break the cycle of addiction
Knowledge-focused OngoingParents with substance use disorders are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including child maltreatment and the intergenerational transmission of addictive disorders. One mechanism linking substance…
Phase: NA • Sponsor: Henry Ford Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New shoulder scale could improve pain assessment
Knowledge-focused CompletedThe purpose of this study is to develop and psychometrically validate the Shoulder Problems Assessment Scale (SPAS), a culturally grounded patient-reported outcome measure designed to assess shoulder-related functional limitations in Turkish adults using a hierarchical stepwise y…
Sponsor: Suleyman Demirel University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Shake or run? study tests best exercise after kidney transplant
Disease control CompletedThis study aimed to compare the effect of whole body vibration versus aerobic training on interleukin 6 and endurance after renal transplantation in patients after renal transplantation.
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Jaw pain mystery: scientists probe genes and feelings for clues
Knowledge-focused ENROLLING_BY_INVITATIONThe aim of this study is to investigate the relationship of psychological aspects, selected blood parameters, pain, central sensitization, and muscle electromyography activity in patients with chronic masticatory muscle pain.
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New study tracks how Weight-Loss surgery resolves diabetes and sleep apnea
Knowledge-focused Recruiting nowThis observational study aims to learn about the correlation between the improving comorbidities associated with obesity after MGB (Mini-Gastric Bypass) surgery and changes in body composition in morbidly obese patients. The main questions it aims to answer are: To study the cor…
Sponsor: All India Institute of Medical Sciences, Bhubaneswar • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Liver biopsy showdown: EUS or needle – patients decide!
Knowledge-focused CompletedPatient Experience in Endohepatology Liver biopsy is a crucial procedure for the diagnosis and/or staging of liver diseases. Common indications for non-targeted biopsies include unexplained elevated liver function tests (LFTs), guiding medical therapy in autoimmune liver diseases…
Sponsor: University Hospital Muenster • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New 3D-Printed feet could let women vets wear any shoes
Symptom relief Recruiting nowVeterans with leg amputations have limited footwear options because their artificial feet do not change shapes for different shoes. Studies have shown that women with amputations receive more frequent prosthetics care than men, but are less satisfied with the fit, comfort, and ap…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Your own tooth could help save your jawbone after extraction
Disease control Completed* The aim of this interventional study is to investigate the dimensional changes in buccolingual alveolar ridge width in socket preservation using sticky dentin vs dentin graft alone * The main question: is dentin graft mixed with autologous fibrin glue has better dimensional cha…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Could stem cell eye drops finally soothe stubborn dry eyes?
Symptom relief OngoingThe goal of this non-randomized, prospective, open, one-arm clinical study is to learn about the clinical efficacy of stem cell eye drops in patients with dry eye disease (DED) who failed to respond to artificial tear sodium hyaluronate eye drops three times a day for two weeks. …
Phase: EARLY_PHASE1 • Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Bubbly water may keep you from fainting
Symptom relief Recruiting nowThe primary purpose of this investigation is to determine whether water carbonation can improve orthostatic tolerance in healthy control volunteers. Orthostatic tolerance refers to the ability to maintain an adequate blood pressure when standing. In some individuals blood pressur…
Phase: NA • Sponsor: Simon Fraser University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Gamified app aims to boost activity in chronic disease patients
Disease control CompletedThe objective of the project is to analyze the clinical effectiveness of a gamifield mHealth application (iGAME) and developed in the context of lifestyle modification, but with the approach of the Behaviour Change Technique, through a randomized clinical trial that affects secon…
Phase: NA • Sponsor: University of Malaga • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Small study finds hope in depression therapy
Symptom relief CompletedThe study is a single-case intervention study, evaluating effects of the treatment Behavioral activation and emotion-focused interventions for depression. Research question and hypothesis 1. What is the effect of behavioural activation and emotion-focused interventions on patie…
Phase: NA • Sponsor: Region Stockholm • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Which insulin works best for Steroid-Induced high blood sugar? new study has answers
Disease control CompletedGlucocorticoids (GC) represent therapeutic agents of great importance in the treatment and prophylaxis of multiple inflammatory and non-inflammatory conditions. Despite their efficacy, the use of GCs is associated with a variety of side effects, one of the immediate ones being th…
Phase: PHASE4 • Sponsor: Max Healthcare Insititute Limited • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Can intermittent fasting help paralyzed veterans lose weight?
Symptom relief ENROLLING_BY_INVITATIONSpinal cord injury (SCI) causes paralysis and muscle atrophy and leads to weight gain and obesity. Obesity directly contributes to functional impairment and cardiometabolic dysfunction. There is a critical need to reduce the growing prevalence of obesity and cardiometabolic disea…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Which nerve block works best for kids' post-surgery pain?
Symptom relief CompletedThe study focuses on comparing the caudal block (CB) and the dorsal penile nerve block (DPNB) via ultrasound guidance in regional anesthesia in hypospadias surgery.
Phase: NA • Sponsor: Ahmed Aouf • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Secondhand cannabis smoke: what gets into your body?
Knowledge-focused Recruiting nowThis is an unblinded pilot study of an environmental exposure to secondhand cannabis smoke in one group of healthy nonsmokers.
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists track coke zero sweetener through the body in 24-Hour urine study
Knowledge-focused CompletedConsumption of beverages containing non-nutritive sweeteners has increased worldwide, but limited information is available regarding the short-term urinary excretion of acesulfame potassium (Ace-K) and the acute metabolic response following consumption of commercially available b…
Phase: NA • Sponsor: Czech University of Life Sciences Prague • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC