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116076 trials found · Page 4477 of 5804
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Simple neck scan may prevent dangerous blood pressure drops in elderly surgery patients
Knowledge-focused Recruiting nowSpinal anesthesia-induced hypotension is a common and clinically significant complication in geriatric patients. Accurate preoperative assessment of intravascular volume status may help identify patients at risk. Internal jugular vein (IJV) ultrasonography is a noninvasive and ea…
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Fat storage mystery: new study probes rare disease
Knowledge-focused Recruiting nowBackground: People with familial partial lipodystrophy (FPLD) do not store fat in the body normally. This can lead to serious illnesses such as diabetes and heart disease. To learn more about FPLD, researchers want to compare the fat tissue in people with this disease to the fat…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Brain boost? L-Citrulline supplement tested for blood flow in aging
Knowledge-focused CompletedThe effect of L-Citrulline is well studied in relation to muscle strength, exhaustion, exercise performance, and endothelial function in health and disease. This study will extend current body of knowledge and will investigate the effect of L-Citrulline on brain vascular function…
Phase: PHASE1 • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Stress-Busting shake? study tests dairy phospholipids for calmer nerves
Symptom relief CompletedThe aim of the study is to investigate the effects of 6- and 12- week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on stress reactivity and recovery in healthy adults. The proposed randomised, double-blind, placebo-controlled paral…
Phase: NA • Sponsor: Northumbria University • Aim: Symptom relief
Last updated Jun 26, 2026 16:38 UTC
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Transgender men and cervical cancer screening: what's holding them back?
Knowledge-focused OngoingIn France, cervical cancer screening is the subject of a national screening programme organized for all asymptomatic individuals aged 25 to 65 years with a cervix. The latter contributes greatly to the prevention and early treatment of this disease, whose public health challenge …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Xanax before eye surgery: a calmer experience?
Symptom relief Recruiting nowThis study aims to explore the effects of anxiety traits on pain, anxiety, and anesthesia satisfaction in patients undergoing cataract surgery under topical anesthesia. On the day of recruitment, patients will complete the BAI, STAI-S, and STAI-T anxiety questionnaires to assess …
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Massive U.S. study to see if whooping cough vaccine is safe for pregnant women and babies
Knowledge-focused OngoingThe purpose of this study is to evaluate the safety of Adacel vaccine among pregnant individuals exposed to Adacel at any point between the 1st day of the 27th week of gestation up to the end of pregnancy and their offspring (ie, Adacel-exposed cohort), in comparison with pregnan…
Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Botox for grinding teeth: does it change jaw muscle over time?
Knowledge-focused CompletedThis study investigates whether repeated botulinum toxin type A (BoNT-A) injections used to manage sleep bruxism lead to structural changes-specifically intramuscular fat accumulation-in the masseter muscle. Adults with probable sleep bruxism receive BoNT-A injections every six m…
Phase: NA • Sponsor: Melek Volkan Yazici • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Heart rehab gets smarter: machine learning tailors exercise to your nerves
Knowledge-focused ENROLLING_BY_INVITATIONCardiac rehabilitation (CR) is an essential secondary prevention component in the treatment of cardiovascular diseases and one of the most cost- effective clinical interventions. Exercise training (ET) in CR programs (CRP) has unequivocal benefits in the reduction of cardiovascul…
Sponsor: Instituto Politécnico de Leiria • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New device could save limbs in sedated ECMO patients
Knowledge-focused Recruiting nowAcute compartment syndrome (ACS) is a surgical emergency that can develop in patients on extracorporeal membrane oxygenation (ECMO). ACS is a type of limb ischemia, which means that the limb, such as the arm or leg, loses blood flow. Patients on ECMO can develop this condition fo…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can a weekly chat with fellow veterans lift depression? small study says maybe.
Symptom relief CompletedVOICES Veterans Socials (VS) support Veterans in the community through weekly social groups. Veterans socials have the potential to improve social functioning, mental health symptoms, and create lasting social support. This project aims to evaluate and improve Veterans Socials to…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Morning or afternoon? study tests best time for COPD exercise
Knowledge-focused Recruiting nowPulmonary rehabilitation (PR) is an effective intervention for reducing hospital readmissions, secondary events, and mortality in patients with respiratory pathologies. The program should not be improved by introducing new subjects such as circadian rhythm.
Phase: NA • Sponsor: Michaël RACODON • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New study sees if Real-World data can track Lecanemab's impact on families
Knowledge-focused ENROLLING_BY_INVITATIONAvailable FDA approved treatments for Alzheimer's disease (AD) temporary alleviate symptoms but have no bearing on overall disease progression. However, recent FDA approval of lecanemab (July 2023), a disease modifying therapy based on a phase 3 clinical trial demonstrated effica…
Sponsor: HealthPartners Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New video series aims to tackle sexual health taboo in breast cancer care
Knowledge-focused CompletedThe purpose of this study is to assess the acceptability, appropriateness, and feasibility of a educational video series for patients going through breast cancer treatment.
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Failed your colonoscopy prep? scientists test three rescue options to find the best clean.
Symptom relief Recruiting nowThe goal of this clinical trial is to learn which rescue bowel preparation works best for adults who need a repeat colonoscopy after a previous bowel preparation did not clean the bowel well enough. The study will also look at how satisfied participants are with each preparation.…
Phase: NA • Sponsor: Ospedale San Pio • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Alcohol may weaken dental anesthesia, new study suggests
Knowledge-focused CompletedThis prospective, randomized, double-blind clinical trial will be carried out Conservative Dentistry, Faculty of Dentistry, Jamia Millia Islamia. Seventy adult patients (35 alcoholic and 35 non-alcoholics) with symptomatic irreversible pulpits in a mandibular first or second mola…
Phase: NA • Sponsor: Jamia Millia Islamia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Strength after breast cancer: new exercise program aims to help survivors recover
Symptom relief Recruiting nowThe goal of this study is to explore whether a group exercise program called Strength After Breast Cancer can be delivered in an outpatient physical therapy clinic to improve physical function among women after treatment for breast cancer. The main questions this study aims to a…
Phase: NA • Sponsor: MGH Institute of Health Professions • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Whey to go? study tests protein drink for sharper memory and better mood
Symptom relief CompletedThe aim of this study is to investigate the effects of 6- and 12-week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on cognitive function and mood in healthy young to middle aged adults. The proposed randomised, double blind, placeb…
Phase: NA • Sponsor: Northumbria University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Can we predict blood cancer in ovarian cancer survivors?
Knowledge-focused Recruiting nowThis study is being done to investigate clonal hematopoiesis and therapy-emergent myeloid neoplasms in patients with ovarian or other solid cancers. Researchers want to identify risk factors for developing these blood cancers as well as if there is/are a genetic/environmental com…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Everyday people also struggle with balance after ACL surgery, study finds
Knowledge-focused CompletedAnterior cruciate ligament (ACL) injuries are among the most frequent knee injuries, often leading to deficits in postural stability and balance as a result of mechanoreceptor damage, which disrupts proprioceptive feedback and sensorimotor regulation. The present study aimed to p…
Sponsor: Nigde Omer Halisdemir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC