New pill aims to tame rare immune diseases
NCT ID NCT06878365
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This early-stage trial tests an experimental drug called BI 3000202 in 16 adults with rare type 1 interferonopathies, such as Aicardi-Goutières syndrome. Participants take a low dose for 4 weeks, then a higher dose for 36 weeks. The main goal is to see if the drug is safe and how the body processes it.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BI 3000202 (an experimental drug taken as tablets)
- What this could lead to
- If it works, this could point toward a treatment that helps control type 1 interferonopathies, rare immune disorders.
- What could go wrong
- This is a very early, small Phase 1 trial with only 16 participants. It primarily tests safety, not effectiveness, so it may not lead to a working treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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ASST degli Spedali Civili di Brescia
Brescia, 25123, Italy
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Azienda Sanitaria Universitaria Giuliano Isontina
Trieste, 34124, Italy
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Barzilai Medical Center
Ashkelon, 7830604, Israel
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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HOP Tenon
Paris, 75020, France
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Hopital Necker
Paris, 75015, France
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hospital Virgen del Rocío
Seville, 41013, Spain
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Hôpital Gui de Chauliac
Montpellier, 34295, France
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Medizinische Hochschule Hannover
Hanover, 30625, Germany
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Royal Free Hospital
London, NW3 2QG, United Kingdom
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Royal Infirmary of Edinburgh
Edinburgh, EH16 4SA, United Kingdom
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Texas Children's Hospital
Houston, Texas, 77030, United States
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ULS de Santa Maria, E.P.E
Lisbon, 1649-035, Portugal
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ULS de Santo Antônio, E.P.E - Centro Hospitalar Universitário de Santo António
Porto, 4099-001, Portugal
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Universitair Ziekenhuis Gent
Ghent, 9000, Belgium
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University of California San Francisco
San Francisco, California, 94143, United States
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Universitätsklinikum Carl Gustav Carus Dresden
Dresden, 01307, Germany
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Universitätsklinikum Tübingen
Tübingen, 72076, Germany
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