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116076 trials found · Page 4113 of 5804
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Spine surgery device under review: does karma fixation deliver?
Knowledge-focused ENROLLING_BY_INVITATIONThe purpose of this observational, multi-center, ambispective study is collect real world patient outcomes that characterize the effectiveness of the Karma Fixation System in the lumbar spine.
Sponsor: Spinal Elements • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Can pool workouts beat gym exercises for back pain?
Symptom relief CompletedThis study aims to learn about the effects of aquatic and land exercises on managing chronic low back pain in adults aged 18-65. The participants engage in a 12-week supervised land and water-based exercise program. The main questions this study aims to answer are: * How effect…
Phase: NA • Sponsor: University of Edinburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Which drug works best for blood pressure drops during emergency surgery?
Disease control TerminatedThe goal of this clinical trial is to compare the efficacy of two vasopressors (norepinephrine vs. ephedrine) in treating hypotension in adult patients (aged 18+, ASA I-III) undergoing general anesthesia for abdominal surgical emergencies (e.g., appendicitis, intestinal obstructi…
Phase: PHASE4 • Sponsor: Hopital Charles Nicolle • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New study tracks hidden virus danger in pregnancy
Knowledge-focused Recruiting nowThe goal of this observational study is to define the rate of intrauterine parvovirus B19 infection and fetal/newborn complications after parvovirus B19 infection of pregnant women. Secondary objectives are risk factors, pregnancy outcomes, long-term sequelae and efficacy of the …
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Dental implant showdown: titanium mesh vs collagen membrane for stronger smiles
Disease control Recruiting nowStatement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone. Aim: The aim of this study is to assess the buccal bone thickness after augmentation w…
Phase: NA • Sponsor: Misr International University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Heart imaging showdown: which software is best for septic shock?
Knowledge-focused Recruiting nowSeptic shock is a critical condition associated with high mortality. Transthoracic echocardiography is widely used to evaluate cardiac function and guide treatment. Left and right atrial strain (LAS and RAS) measured via speckle tracking echocardiography have shown prognostic val…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New support group aims to ease stress for black Alzheimer's caregivers
Symptom relief CompletedBlack family caregivers of older adults with Alzheimer's disease and/or related dementias (ADRD), have an increased mortality risk related to pre-existing health conditions and stress. Targeted, culturally responsive, health interventions that help Black ADRD caregivers to effect…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Knee surgery showdown: cement vs. no cement for stronger bones
Knowledge-focused Recruiting nowThe purpose of this study is to examine femur bone mineral density (BMD) change before and after surgery in patients receiving cemented or cementless total knee arthroplasty (TKA). performed with manual or robotic methods. 100 participants will be enrolled and can expect to be on…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Can an online course help first responders sleep better?
Symptom relief Recruiting nowThis study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the Sleep Course, adapted for public safety personnel (PSP) experiencing sleep difficulties. The study seeks to replicate prior results from an Australian version …
Phase: NA • Sponsor: University of Regina • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New study seeks better pain relief after minimally invasive heart surgery
Symptom relief CompletedOptimization of postoperative analgesia and reduction of opioid consumption are key components of Enhanced Recovery After Surgery (ERAS) protocols in cardiac surgery. Although intravenous opioids have traditionally been the mainstay of analgesic management due to their potent ana…
Phase: NA • Sponsor: Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Pre-Surgery IV placement could save time and money for patients with difficult veins
Knowledge-focused OngoingOur goal is to demonstrate how a standardized approach that involves the pre-operative implantation of the venous access devices in the DIVA patients (EA-DIVA score\> or =8), scheduled for orthopedic surgery, impacts both the intra- and post-operative safety of the patient and th…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New tapping therapy shows promise for trauma relief
Symptom relief CompletedThe purpose of this retrospective study was to evaluate the effectiveness of a new psychotherapy technique called Psychological Cognitive Reprocessing Procedure (P-CRP) in treating trauma symptoms. The P-CRP intervention was developed and manualized by the principal investigator …
Phase: NA • Sponsor: Zahide Betül Baydar • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Home workouts tested for Arthritis-Lung condition
Symptom relief CompletedThis study aimed to evaluate the effectiveness of asynchronously implemented telerehabilitation-supported respiratory physiotherapy and function-oriented trunk stabilization exercises, which have not been previously applied in individuals with RA-IAH.
Phase: NA • Sponsor: Zülal TATAR • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Can a smartphone app accurately measure depression?
Knowledge-focused Recruiting nowThe aim of this clinical investigation is to find out whether the EMOCARE emotional monitoring software provides consistent results compared with the tools available for assessing the emotional state of patients suffering from mild to moderately severe depressive episod. It will …
Phase: NA • Sponsor: Emobot • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New dissolvable nail aims to fix knee fractures without metal hardware
Disease control ENROLLING_BY_INVITATIONThe OSSIOfiber® Trimmable Fixation Nails are indicated for maintenance of alignment and fixation of bone fractures, osteotomies, arthrodesis and bone grafts in the presence of appropriate additional immobilization (e.g., rigid fixation implants, cast, brace). Our hypothesis is th…
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Can group therapy tailored for turkish students ease emotional struggles?
Symptom relief Recruiting nowUniversity students' psychological well-being is a growing public health concern. University life involves major psychological, social, and academic changes, increasing vulnerability to mental health issues. Group-based Dialectical Behaviour Therapy (DBT) has been shown to suppor…
Phase: NA • Sponsor: Bogazici University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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New dental bone material put to the test in 80 patients
Disease control OngoingThis study aims to collect real-world clinical data to gather information on the performance and safety of the TriOSS® when used according to its intended purpose and current clinical applications. The results of the clinical study will serve as clinical evidence for the device's…
Sponsor: Bioceramed • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a smartphone app help prevent suicide? new study investigates
Knowledge-focused CompletedThe central purpose of this project is to evaluate and facilitate access to evidence-based best practices for individuals struggling with suicidal ideation and co-occurring behavioral problems, including alcohol misuse, and provide assistance to the patients while they are waitin…
Phase: NA • Sponsor: Evidence-Based Practice Institute, Seattle, WA • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Therapy boosts emotional skills in vulnerable kids
Symptom relief OngoingThe general objective of this study is to determine the effects of an emotion-focused therapy-based group social work intervention on the emotion regulation skills, emotional intelligence, and empathic tendency levels of children aged 9-11 years in need of protection and living i…
Phase: NA • Sponsor: Selcuk University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Oxygen therapy may boost stem cells – new study investigates
Knowledge-focused Recruiting nowHematopoietic stem cells (HSCs), which govern the production of all blood lineages, transition through a series of functional states characterized by expansion during fetal development, functional quiescence in adulthood, and decline upon aging. Although research on aging has fo…
Phase: NA • Sponsor: Assaf-Harofeh Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC