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Twenty patients with non restorable maxillary molar that indicate to immediate implant will be included in this study. The patients will be divided randomly (10 patients each group). Group I(study),immediate implant placement will be done using root guide technique.Group II(contr…

This study aims to investigate the acute effects of Tribulus terrestris supplementation on anaerobic performance and sprint times in trained male combat sport athletes. A total of 28 athletes from kickboxing, Muay Thai, and taekwondo disciplines will participate in a randomized, …

PREDICT REFINE is a sub-study of PREDICT 3 with the primary aim of exploring glycemic responses through continuous glucose monitoring in a healthy population. The study will explore glycemic responses to a standardised test meal before and after a personalised dietary programme. …

This study investigates whether vaginal estrogen treatment has an effect on hemostatic parameters in postmenopausal women. Blood samples are collected before and after 3 months treatment to assess changes in hemostasis.

This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults. The study includes all adult patients admitted in 2024 to the ICU Ward B …

The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery. This would allow physicians to identify which patient could benefit the most from fluid expansion, thus avoiding useless and potential…

Mixed Martial Arts (MMA) is a physically demanding sport that requires athletes to maintain high levels of strength, flexibility, rapid response, and power. However, the intense focus on strength and endurance training in MMA can often result in neglecting joint health, flexibili…

This study will be randomized clinical trial and will recruit male soccer players aged 18-30yrs.Participants will be randomly divided into two groups with each group performing their program 3 times per week for 8 weeks.Group A will engage in Accentuated Eccentric resistance trai…

High-Intensity Interval Training (HIIT) and Medium-Intensity Interval Training (MIIT) are popular training methods known for enhancing athletic performance. HIIT is characterized by short bursts of high-intensity exercise followed by brief recovery periods. This training approach…

This is a randomized clinical trial will recruit male football players aged 18-30 years who regularly participated in sports more than 3 years, with a BMI between 18.5-24.9 kg/m².Athletes with smoking habits, those following other specialized training programs, or those taking an…

This study will compare the effects of Moderate-Intensity Circuit Training (MICT) and Moderate-Intensity Continuous Training (MICT) on Heart rate recovery, VO₂ max, power, and agility in 40 male soccer players aged 18-25. Participants will be randomly assigned to either group, wi…

The physical demands of patient transport, including lifting and transferring patients, are significant contributors to the high risk of musculoskeletal disorders. Previous studies have demonstrated that these workers frequently experience musculoskeletal pain. Although current p…

A Pilot Study to Determine the Impact of the Phoenix Wound Matrix® on the Wound Microbiome in Chronic Diabetic Foot Ulcers

Breast cancer is one of the tumors with the highest incidence and current evidence indicates a higher prevalence in elderly patients (≥70 years) with a higher mortality rate due to immunosenescence, diagnostic delay and under treatment. Elderly patients are still poorly represent…

This behavioral clinical trial evaluates an adaptively tailored, mobile phone-delivered intervention (MOSAIC) designed to support adults managing their type 2 diabetes. Adaptive means the intervention can change over time. Tailored means the intervention may be different for diff…

Total hysterectomy is one of the most common surgical procedures in gynecology. Total laparoscopic hysterectomy (TLH) has several advantages over open surgery, such as better cosmetic outcomes, faster recovery, and an earlier return to normal activities and work, and has thus bec…

There has been much interest in the potential role of social media (SM) use in driving a current mental health crisis among teens, with a dire need for evidence that goes beyond self-report. One important avenue is to understand the role of the brain in driving the effects of SM …

The Italian population is progressively aging, and cancer incidence increases with age. Older patients are at higher risk of frailty, a condition associated with adverse outcomes such as disability, falls, hospitalization, and mortality. Key indicators of frailty include reduced…

The purpose of this study to evaluate the effectiveness, safety, and tolerability of SUZ as part of multimodal therapy (MMT) in treating acute postoperative pain.

This single-center randomized controlled trial aims to investigate the effects of transcutaneous auricular vagus nerve stimulation on the acute stress responses. The primary aim of this study is to assess the efficacy of taVNS in mitigating the acute stress response induced by the…